N-(m-PEG4)-N'-(PEG2-NHS ester)-Cy5

Modify Date: 2024-01-10 18:11:25

N-(m-PEG4)-N'-(PEG2-NHS ester)-Cy5 structure	Common Name	N-(m-PEG4)-N'-(PEG2-NHS ester)-Cy5
	CAS Number	2107273-28-7	Molecular Weight	838.43
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₄₅H₆₀ClN₃O₁₀	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of N-(m-PEG4)-N'-(PEG2-NHS ester)-Cy5

N-(m-PEG4)-N'-(PEG2-NHS ester)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	N-(m-PEG4)-N'-(PEG2-NHS ester)-Cy5

Description	N-(m-PEG4)-N'-(PEG2-NHS ester)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula	C₄₅H₆₀ClN₃O₁₀
Molecular Weight	838.43

Hazard Codes	Xi