Dibenzo[c,h]acridine

Modify Date: 2024-01-10 14:23:23

Dibenzo[c,h]acridine Structure
Dibenzo[c,h]acridine structure
Common Name Dibenzo[c,h]acridine
CAS Number 224-53-3 Molecular Weight 279.335
Density 1.3±0.1 g/cm3 Boiling Point 534.0±19.0 °C at 760 mmHg
Molecular Formula C21H13N Melting Point 191ºC
MSDS N/A Flash Point 240.3±14.1 °C

 Names

Name Dibenz[c,h]acridine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 534.0±19.0 °C at 760 mmHg
Melting Point 191ºC
Molecular Formula C21H13N
Molecular Weight 279.335
Flash Point 240.3±14.1 °C
Exact Mass 279.104797
PSA 12.89000
LogP 5.86
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.824
Storage condition 2-8°C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
HN1225000
CHEMICAL NAME :
Dibenz(c,h)acridine
CAS REGISTRY NUMBER :
224-53-3
BEILSTEIN REFERENCE NO. :
0209259
LAST UPDATED :
199612
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C21-H13-N
MOLECULAR WEIGHT :
279.35
WISWESSER LINE NOTATION :
T E6 D6 B666 CNJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2040 mg/kg/85W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
4400 mg/kg/65W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
300 mg/kg/25W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
4 ug/plate
REFERENCE :
BJCAAI British Journal of Cancer. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants. RG21 2XS, UK) V.1- 1947- Volume(issue)/page/year: 37,873,1978 *** REVIEWS *** TOXICOLOGY REVIEW 85DHAX "Medical and Biologic Effects of Environmental Pollutants Series," Washington, DC, National Academy of Sciences, 1972-77 Volume(issue)/page/year: Pc,4,1972

 Safety Information

HS Code 2933990090

 Synthetic Route

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles1

More Articles
Dose-dependent differences in the profile of mutations induced by carcinogenic (R,S,S,R) bay- and fjord-region diol epoxides of polycyclic aromatic hydrocarbons.

Adv. Exp. Med. Biol. 500 , 697-707, (2001)

Chinese hamster V79 cells were exposed to a high or low concentration of the highly carcinogenic (R,S,S,R) or the less active (S,R,R,S) bay- or fjord-region diol epoxides of benzo[a]pyrene, benzo[c]ph...

 Synonyms

Dibenzo[c,h]acridine
1,2:7,8-dibenzacridine
Dibenz[c,h]acridine
3,4,5,6-dibenzacridine