Dopamine D3 receptor ligand-4

Modify Date: 2024-04-05 20:21:30

Dopamine D3 receptor ligand-4 structure	Common Name	Dopamine D3 receptor ligand-4
	CAS Number	2376333-77-4	Molecular Weight	444.59
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₆H₂₈N₄OS	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Dopamine D3 receptor ligand-4

Dopamine D3 receptor ligand-4 (compound 6) is a potent and selective dopamine D3 receptor ligand, with a Ki of 0.5 nM. Dopamine D3 receptor ligand-4 shows high level of selectivity for D3 over D2 (Ki=7.43 nM). Dopamine D3 receptor ligand-4 can be used for the research of Cocaine use disorder[1].

Name	Dopamine D3 receptor ligand-4

Description	Dopamine D3 receptor ligand-4 (compound 6) is a potent and selective dopamine D3 receptor ligand, with a Ki of 0.5 nM. Dopamine D3 receptor ligand-4 shows high level of selectivity for D3 over D2 (Ki=7.43 nM). Dopamine D3 receptor ligand-4 can be used for the research of Cocaine use disorder[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Dopamine Receptor Signaling Pathways >> Neuronal Signaling >> Dopamine Receptor Research Areas >> Neurological Disease
Target	D3 Receptor:0.5 nM (Ki) D2 Receptor:7.43 nM (Ki)
References	[1]. Blass BE, et al. Design, synthesis, and evaluation of functionalized 5-(4-arylpiperazin-1-yl)-N-arylpentanamides as selective dopamine D3 receptor ligands. Med Chem Res 31, 132-145 (2022).

Molecular Formula	C₂₆H₂₈N₄OS
Molecular Weight	444.59

Dopamine D3 receptor ligand-4

Use of Dopamine D3 receptor ligand-4

Names

Dopamine D3 receptor ligand-4 Biological Activity

Chemical & Physical Properties