HCV-IN-37

Modify Date: 2024-01-14 14:25:52

HCV-IN-37 Structure
HCV-IN-37 structure
Common Name HCV-IN-37
CAS Number 2425804-98-2 Molecular Weight 515.64
Density N/A Boiling Point N/A
Molecular Formula C31H35F2N5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of HCV-IN-37


HCV-IN-37 (Compound 3d) is a potent inhibitor of HCV. HCV-IN-37 is orally available and long-lasting in rat plasma after oral administration to rats by a single dose of 15 mg/kg. The high potency of active derivative HCV-IN-37 is primarily driven by the inhibitory effect on the virus entry stage[1].

 Names

Name HCV-IN-37

 HCV-IN-37 Biological Activity

Description HCV-IN-37 (Compound 3d) is a potent inhibitor of HCV. HCV-IN-37 is orally available and long-lasting in rat plasma after oral administration to rats by a single dose of 15 mg/kg. The high potency of active derivative HCV-IN-37 is primarily driven by the inhibitory effect on the virus entry stage[1].
Related Catalog
Target

EC50: 0.005 ± 0.005 μM (HCV)[1]

References

[1]. Wang Y, et al. Design, Synthesis, and Biological Evaluation of 2-((4-Bisarylmethyl-piperazin-1-yl)methyl)benzonitrile Derivatives as HCV Entry Inhibitors. J Med Chem. 2022 Feb 10;65(3):2107-2121.

 Chemical & Physical Properties

Molecular Formula C31H35F2N5
Molecular Weight 515.64