3,4,5-Trihydroxy(2H2)benzoic acid

Modify Date: 2024-01-02 19:15:42

3,4,5-Trihydroxy(2H2)benzoic acid structure	Common Name	3,4,5-Trihydroxy(2H2)benzoic acid
	CAS Number	294660-92-7	Molecular Weight	172.132
	Density	1.7±0.1 g/cm3	Boiling Point	501.1±50.0 °C at 760 mmHg
	Molecular Formula	C₇H₄D₂O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	271.0±26.6 °C

Use of 3,4,5-Trihydroxy(2H2)benzoic acid

Gallic acid-d2 is the deuterium labeled Gallic acid[1]. Gallic acid (3,4,5-Trihydroxybenzoic acid) is a natural polyhydroxyphenolic compound and an free radical scavenger to inhibit cyclooxygenase-2 (COX-2)[2]. Gallic acid has various activities, such as antimicrobial, antioxidant, antimicrobial, anti-inflammatory, and anticance activities[3].

Name	3,4,5-trihydroxybenzoic-2,6-d2 acid
Synonym	More Synonyms

Description	Gallic acid-d2 is the deuterium labeled Gallic acid[1]. Gallic acid (3,4,5-Trihydroxybenzoic acid) is a natural polyhydroxyphenolic compound and an free radical scavenger to inhibit cyclooxygenase-2 (COX-2)[2]. Gallic acid has various activities, such as antimicrobial, antioxidant, antimicrobial, anti-inflammatory, and anticance activities[3].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Signaling Pathways >> Apoptosis >> Ferroptosis Signaling Pathways >> Immunology/Inflammation >> COX
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Amaravani M, et al. COX-2 structural analysis and docking studies with gallic acid structural analogues. Springerplus. 2012 Dec;1(1):58. [3]. Bak EJ, et al. Gallic acid improves glucose tolerance and triglyceride concentration in diet-induced obesity mice. Scand J Clin Lab Invest. 2013 Dec73(8):607-14. [4]. Cheng Y, et al. Plant Natural Products Calycosin and Gallic Acid Synergistically Attenuate Neutrophil Infiltration and Subsequent Injury in Isoproterenol-Induced Myocardial Infarction: A Possible Role for Leukotriene B4 12-Hydroxydehydrogenase? Oxid Med Cell Longev. 20152015:434052.

Density	1.7±0.1 g/cm3
Boiling Point	501.1±50.0 °C at 760 mmHg
Molecular Formula	C₇H₄D₂O₅
Molecular Weight	172.132
Flash Point	271.0±26.6 °C
Exact Mass	172.034073
PSA	97.99000
LogP	0.91
Vapour Pressure	0.0±1.4 mmHg at 25°C
Index of Refraction	1.730

3,4,5-Trihydroxy(H)benzoic acid

Benzoic-2,6-d acid, 3,4,5-trihydroxy-

3,4,5-Trihydroxy(2H2)benzoic acid

Use of 3,4,5-Trihydroxy(2H2)benzoic acid

Names

3,4,5-Trihydroxy(2H2)benzoic acid Biological Activity

Chemical & Physical Properties

Synonyms