(R)-TCO-OH

Modify Date: 2024-01-04 11:16:52

(R)-TCO-OH Structure
(R)-TCO-OH structure
Common Name (R)-TCO-OH
CAS Number 39637-78-0 Molecular Weight 126.20
Density N/A Boiling Point N/A
Molecular Formula C8H14O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (R)-TCO-OH


(R)-TCO-OH is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name (R)-TCO-OH

 (R)-TCO-OH Biological Activity

Description (R)-TCO-OH is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl-Chain

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Molecular Formula C8H14O
Molecular Weight 126.20