(Z)-p-cyano-α-Cyanostilbene

Modify Date: 2024-04-03 12:50:34

(Z)-p-cyano-α-Cyanostilbene structure	Common Name	(Z)-p-cyano-α-Cyanostilbene
	CAS Number	54676-54-9	Molecular Weight	230.26
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₆H₁₀N₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of (Z)-p-cyano-α-Cyanostilbene

(Z)-p-cyano-α-Cyanostilbene (compound 11), a phenantrene derivative, has antiproliferative activity. (Z)-p-cyano-α-Cyanostilbene shows significant selectivity against HeLa (IC50=0.21 µM) and HepG2 (IC50=0.230 µM) cells without cytotoxic against normal skin fibroblasts (IC50>100 µM)[1].

Name	(Z)-4-(1-cyano-2-phenylvinyl)benzonitrile
Synonym	More Synonyms

Description	(Z)-p-cyano-α-Cyanostilbene (compound 11), a phenantrene derivative, has antiproliferative activity. (Z)-p-cyano-α-Cyanostilbene shows significant selectivity against HeLa (IC50=0.21 µM) and HepG2 (IC50=0.230 µM) cells without cytotoxic against normal skin fibroblasts (IC50>100 µM)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Nataša Perin, et al. Antiproliferative activity and mode of action analysis of novel amino and amido substituted phenantrene and naphtho[2,1-b]thiophene derivatives. Eur J Med Chem. 2020 Jan 1;185:111833.

Molecular Formula	C₁₆H₁₀N₂
Molecular Weight	230.26
Exact Mass	230.08400
PSA	47.58000
LogP	3.62246

4-(1-cyano-2-phenylvinyl)benzonitrile

4-((Z)-1-Cyano-2-phenyl-vinyl)-benzonitrile

(Z)-p-cyano-α-Cyanostilbene

Use of (Z)-p-cyano-α-Cyanostilbene

Names

(Z)-p-cyano-α-Cyanostilbene Biological Activity

Chemical & Physical Properties

Synonyms