4-amino-1-methyl-2-phenyl-5-trideuteriomethyl-1,2-dihydro-pyrazol-3-one

Modify Date: 2024-01-09 22:57:02

4-amino-1-methyl-2-phenyl-5-trideuteriomethyl-1,2-dihydro-pyrazol-3-one Structure
4-amino-1-methyl-2-phenyl-5-trideuteriomethyl-1,2-dihydro-pyrazol-3-one structure
Common Name 4-amino-1-methyl-2-phenyl-5-trideuteriomethyl-1,2-dihydro-pyrazol-3-one
CAS Number 68229-55-0 Molecular Weight 206.25900
Density N/A Boiling Point N/A
Molecular Formula C11H10D3N3O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 4-amino-1-methyl-2-phenyl-5-trideuteriomethyl-1,2-dihydro-pyrazol-3-one


Ampyrone-d3-1 is the deuterium labeled Ampyrone. Ampyrone is a reagent for glucose determination in the presence of peroxidase and phenol.

 Names

Name 4-amino-1-methyl-2-phenyl-5-trideuteriomethyl-1,2-dihydro-pyrazol-3-one
Synonym More Synonyms

  Biological Activity

Description Ampyrone-d3-1 is the deuterium labeled Ampyrone. Ampyrone is a reagent for glucose determination in the presence of peroxidase and phenol.
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223.

[2]. Berno CR, et al. 4-Aminoantipyrine reduces toxic and genotoxic effects of doxorubicin, cisplatin, and cyclophosphamide in male mice. Mutat Res Genet Toxicol Environ Mutagen. 2016 Jul;805:19-24.

 Chemical & Physical Properties

Molecular Formula C11H10D3N3O
Molecular Weight 206.25900
Exact Mass 206.12500
PSA 52.95000
LogP 1.64780

 Synonyms

3-CD3-4-Aminoantipyrin
4-AMINOANTIPYRINE-D3