GSK345931A

Modify Date: 2024-01-03 20:22:49

GSK345931A structure	Common Name	GSK345931A
	CAS Number	869499-38-7	Molecular Weight	403.83
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₂H₁₉ClNNaO₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of GSK345931A

GSK345931A is an EP1 receptor antagonist. GSK345931A shows measurable CNS penetration in the mouse and rat and potent analgesic efficacy in acute and sub-chronic models of inflammatory pain[1].

Name	sodium,6-[2-[5-chloro-2-(2-methylpropoxy)phenyl]phenyl]pyridine-2-carboxylate
Synonym	More Synonyms

Description	GSK345931A is an EP1 receptor antagonist. GSK345931A shows measurable CNS penetration in the mouse and rat and potent analgesic efficacy in acute and sub-chronic models of inflammatory pain[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Prostaglandin Receptor Research Areas >> Inflammation/Immunology Research Areas >> Neurological Disease
Target	EP1
References	[1]. Hall A, et al. Discovery of GSK345931A: An EP(1) receptor antagonist with efficacy in preclinical models of inflammatory pain. Bioorg Med Chem Lett. 2009 Jan 15;19(2):497-501.

Molecular Formula	C₂₂H₁₉ClNNaO₃
Molecular Weight	403.83
Exact Mass	403.09500
PSA	62.25000
LogP	4.46730

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