<生产厂家 价格>

7-Deaza-2′-deoxyguanosine 5′-triphosphate

用途

7-Deaza-2′-deoxyguanosine 5′-triphosphate (7-Deaza-2'-dGTP) 是一种核苷酸类似物,是一种端粒酶抑制剂 (IC50: 11μM)。

名称

[ CAS 号 ]:
101515-08-6

[ 英文名 ]:
7-Deaza-2′-deoxyguanosine 5′-triphosphate

[英文别名 ]:

生物活性

[ 描述 ]:

7-Deaza-2′-deoxyguanosine 5′-triphosphate (7-Deaza-2'-dGTP) 是一种核苷酸类似物,是一种端粒酶抑制剂 (IC50: 11μM)。

[ 相关类别 ]:

研究领域 >> 癌症
信号通路 >> 细胞周期/DNA损伤 >> 端粒酶

[参考文献]

[1]. Fletcher TM, et al. Human telomerase inhibition by 7-deaza-2'-deoxypurine nucleoside triphosphates. Biochemistry. 1996 Dec 10;35(49):15611-7.  

物理化学性质

[ 密度 ]:
2.48 g/cm3

[ 沸点 ]:
907.1ºC at 760 mmHg

[ 分子式 ]:
C11H16LiN4O13P3

[ 分子量 ]:
512.12600

[ 闪点 ]:
502.4ºC

[ 精确质量 ]:
512.00900

[ PSA ]:
298.24000

[ LogP ]:
0.31790

[ 蒸汽压 ]:
1.76E-35mmHg at 25°C

[ 折射率 ]:
1.854

安全信息

[ 危险品运输编码 ]:
NONH for all modes of transport

文献

Serotonin transporter (5-HTTLPR) and norepinephrine transporter (NET) gene polymorphisms: susceptibility and treatment response of electroconvulsive therapy in treatment resistant depression.

Neurosci. Lett. 590 , 116-20, (2015)

Serotonin transporter (5-HTTLPR) and norepinephrine transporter (NET182C) polymorphisms are associated with susceptibility and treatment response in major depressive disorder (MDD). Thus, we examined ...

5-HTTLPR genotype, asthma, diabetes and late-life depression in an older French population.

Int. J. Geriatr. Psychiatry 30 , 1017-22, (2015)

Associations between environmental risk factors and depression have been reported to be stronger in people with the S allele of the S/L polymorphism in the serotonin transporter gene-linked promoter r...

Clinicopathologic report of ocular involvement in ALS patients with C9orf72 mutation.

Amyotroph. Lateral Scler. Frontotemporal Degener. 15(7-8) , 569-80, (2014)

Our objective was to present clinicopathologic evidence of anterior visual pathway involvement in patients with amyotrophic lateral sclerosis (ALS) secondary to a C9orf72 mutation. Two related patient...


更多文献

推荐生产厂家/供应商:


相关化合物

CAS号[101515-08-6]化源网提供[7-Deaza-2′-deoxyguanosine 5′-triphosphate]MSDS、说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。>>电脑版:7-Deaza-2′-deoxyguanosine 5′-triphosphate

标题:【7-Deaza-2′-deoxyguanosine 5′-triphosphate】7-Deaza-2′-deoxyguanosine 5′-triphosphate CAS号:101515-08-6【结构式 性质 活性】-化源网 地址:https://www.chemsrc.com/amp/cas/101515-08-6_701984.html