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吩嗪硫酸乙酯

吩嗪硫酸乙酯用途

吩嗪乙醇硫酸盐是一种阳离子染料(Ex=390nm,Em=530nm)和电子受体,可用于染料连接酶测定。吩嗪乙醇硫酸盐是在抗坏血酸存在下检测一氧化氮还原酶(Nors)活性的中间体[1][2][3]。

吩嗪硫酸乙酯名称

[ CAS 号 ]:
10510-77-7

[ 中文名 ]:
吩嗪乙基硫酸盐

[ 英文名 ]:
5-Ethylphenazin-5-ium ethyl sulfate

[中文别名 ]:

[英文别名 ]:

EINECS 234-044-9
MFCD00050286
5-Ethylphenazin-5-ium ethyl sulfate
5-ethylphenazin-5-ium,ethyl sulfate

吩嗪硫酸乙酯生物活性

[ 描述 ]:

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[参考文献]

[1]. R Ghosh, et al. Phenazine ethosulfate as a preferred electron acceptor to phenazine methosulfate in dye-linked enzyme assays. Anal Biochem. 1979 Oct 15;99(1):112-7.

[2]. O.A.Ryazanova, et al. pH-Induced changes in electronic absorption and fluorescence spectra of phenazine derivatives. Spectrochim Acta A Mol Biomol Spectrosc. 2007 Apr;66(4-5):849-59.

[3]. Jessica H van Wonderen, et al. The nitric oxide reductase activity of cytochrome c nitrite reductase from Escherichia coli. J Biol Chem. 2008 Apr 11;283(15):9587-94.

吩嗪硫酸乙酯物理化学性质

[ 熔点 ]:
190℃

[ 分子式 ]:
C₁₆H₁₈N₂O₄S

[ 分子量 ]:
334.390

[ 精确质量 ]:
334.098724

[ PSA ]:
91.58000

[ LogP ]:
3.25930

[ 储存条件 ]:
-20℃，干燥，密封

吩嗪硫酸乙酯MSDS

吩嗪硫酸乙酯毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SG1635000

CHEMICAL NAME :: Phenazinium, 5-ethyl-, ethylsulfate

CAS REGISTRY NUMBER :: 10510-77-7

LAST UPDATED :: 199701

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C14-H13-N2.C2-H5-O4-S

MOLECULAR WEIGHT :: 334.42

WISWESSER LINE NOTATION :: T C666 CK INJ C2 &WSO&O2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 100 ug/plate

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 40,203,1976

吩嗪硫酸乙酯安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi: Irritant;

[ 风险声明 (欧洲) ]:
36/37/38

[ 安全声明 (欧洲) ]:
S26;S36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ RTECS号 ]:
SG1635000

[ 海关编码 ]:
2933990090

吩嗪硫酸乙酯合成路线

吩嗪硫酸乙酯上下游产品

吩嗪硫酸乙酯上游产品

吩嗪硫酸乙酯下游产品

吩嗪硫酸乙酯海关

[ 海关编码 ]: 2933990090

[ 中文概述 ]:
2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

吩嗪硫酸乙酯文献

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Int. J. Hematol. 102 , 327-34, (2015)

Indoleamine 2,3-dioxygenase (IDO) catalyzes the rate-limiting step in the metabolism of tryptophan along the kynurenine pathway. In tumors, increased IDO activity inhibits proliferation and induces ap...

The anti-lymphoma activity of APO866, an inhibitor of nicotinamide adenine dinucleotide biosynthesis, is potentialized when used in combination with anti-CD20 antibody.

Leuk. Lymphoma 55(9) , 2141-50, (2014)

APO866 is an inhibitor of nicotinamide adenine dinucleotide (NAD) biosynthesis that exhibits potent anti-lymphoma activity. Rituximab (RTX), an anti-CD20 antibody, kills lymphoma cells by direct apopt...

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