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5-甲基吩嗪硫酸甲酯

5-甲基吩嗪硫酸甲酯用途

甲基硫酸吩嗪是一种自由基发生器。甲基硫酸奋乃静作为电子转移反应物用于细胞活力测定。甲基硫酸奋乃静在还原剂NADPH存在下诱导ssDNA断裂。碱性彗星试验中甲基硫酸奋乃静诱导DNA氧化损伤和细胞凋亡。

5-甲基吩嗪硫酸甲酯名称

[ CAS 号 ]:
299-11-6

[ 中文名 ]:
5-甲基吩嗪硫酸甲酯

[ 英文名 ]:
Phenazine methylsulfate

[中文别名 ]:

[英文别名 ]:

EINECS 206-072-1
5-methylphenylazinium methyl sulfate
PHENAZINE METHOLSULPHATE
Phenazine Methyl Sulfate
N-methyl phenazinium methylsulphate
Phenazine Methoshlphate
PMS,phenazine methosulfate
Phenazinium, 5-methyl-, methyl sulfate
5-methylphenazinium methylsulfate
5-Methylphenazinium methosulfate

5-甲基吩嗪硫酸甲酯生物活性

[ 描述 ]:

[ 相关类别 ]:

信号通路 >> 细胞凋亡 >> 细胞凋亡

信号通路 >> 抗感染 >> 细菌

5-甲基吩嗪硫酸甲酯物理化学性质

[ 熔点 ]:
158-160 °C (dec.)(lit.)

[ 分子式 ]:
C₁₄H₁₄N₂O₄S

[ 分子量 ]:
306.337

[ 精确质量 ]:
306.067413

[ PSA ]:
91.58000

[ LogP ]:
2.38630

[ 外观性状 ]:
黄色结晶

[ 储存条件 ]:
2-8°C

[ 稳定性 ]:
Stable. Incompatible with strong oxidizing agents.

[ 水溶解性 ]:
soluble

5-甲基吩嗪硫酸甲酯MSDS

5-甲基吩嗪硫酸甲酯毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SG1645000

CHEMICAL NAME :: Phenazinium, 5-methyl-, methylsulfate

CAS REGISTRY NUMBER :: 299-11-6

LAST UPDATED :: 199701

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C13-H11-N2.C-H3-O4-S

MOLECULAR WEIGHT :: 306.36

WISWESSER LINE NOTATION :: T C666 BK INJ B1 &WSO&O1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 19 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: DNA adduct

TEST SYSTEM :: Fish - salmon Sperm

DOSE/DURATION :: 3300 nmol/L

REFERENCE :: BICHAW Biochemistry. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) V.1- 1962- Volume(issue)/page/year: 8,1238,1969 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X3658 No. of Facilities: 194 (estimated) No. of Industries: 1 No. of Occupations: 5 No. of Employees: 2761 (estimated) No. of Female Employees: 2298 (estimated)

5-甲基吩嗪硫酸甲酯安全信息

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xn:Harmful;

[ 风险声明 (欧洲) ]:
R36/37/38;R68

[ 安全声明 (欧洲) ]:
S26-S36/37/39

[ 危险品运输编码 ]:
2811

[ WGK德国 ]:
3

[ RTECS号 ]:
SG1645000

[ 海关编码 ]:
2933990090

5-甲基吩嗪硫酸甲酯合成路线

5-甲基吩嗪硫酸甲酯上下游产品

5-甲基吩嗪硫酸甲酯上游产品

5-甲基吩嗪硫酸甲酯下游产品

5-甲基吩嗪硫酸甲酯海关

[ 海关编码 ]: 2933990090

[ 中文概述 ]:
2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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To investigate the suitability of three antimicrobial peptides (AMPs) as cell-penetrating antimicrobial peptides.Cellular uptake of three AMPs (PK-12-KKP, SA-3 and TPk) and a cell-penetrating peptide ...

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