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N-羟乙酰神经氨酸

N-羟乙酰神经氨酸用途

N-Glycolylneuraminic acid 是一种非人唾液酸分子,是可以在猪中合成但在人类中不合成的。N-Glycolylneuraminic acid 作为结合甲型流感病毒 (IAVs) 的诱饵受体起作用。

N-羟乙酰神经氨酸名称

[ CAS 号 ]:
1113-83-3

[ 中文名 ]:
N-羟乙酰神经氨酸

[ 英文名 ]:
N-Glycolylneuraminic acid

[英文别名 ]:

Neuraminic acid, N-glycolyl-
NGNA
NeuNGl
N-Glycolylneuraminate
N-glycoloyl-β-neuraminic acid
N-GLYCOLYNEURAMINIC ACID
GcNeu
N-Glycolyl Neuraminic Acid
MFCD00057551
N-glycoylneuraminic acid

N-羟乙酰神经氨酸生物活性

[ 描述 ]:

[ 相关类别 ]:

信号通路 >> 抗感染 >> 流感病毒

研究领域 >> 炎症/免疫

[参考文献]

[1]. Takahashi T, et al. N-glycolylneuraminic acid on human epithelial cells prevents entry of influenza A viruses that possess N-glycolylneuraminic acid binding ability. J Virol. 2014 Aug;88(15):8445-56.

N-羟乙酰神经氨酸物理化学性质

[ 密度 ]:
1.9±0.1 g/cm3

[ 沸点 ]:
826.1±75.0 °C at 760 mmHg

[ 熔点 ]:
188-190°C

[ 分子式 ]:
C₁₁H₁₉NO₁₀

[ 分子量 ]:
325.269

[ 闪点 ]:
453.4±37.1 °C

[ 精确质量 ]:
325.100891

[ PSA ]:
197.01000

[ LogP ]:
-2.96

[ 外观性状 ]:
白色至灰白色粉末

[ 蒸汽压 ]:
0.0±0.6 mmHg at 25°C

[ 折射率 ]:
1.651

[ 储存条件 ]:
−20°C

N-羟乙酰神经氨酸MSDS

详细MSDS(安全技术说明书)

N-羟乙酰神经氨酸安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xi

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

N-羟乙酰神经氨酸文献

The role of sialyl glycan recognition in host tissue tropism of the avian parasite Eimeria tenella.

PLoS Pathog. 7(10) , e1002296, (2011)

Eimeria spp. are a highly successful group of intracellular protozoan parasites that develop within intestinal epithelial cells of poultry, causing coccidiosis. As a result of resistance against antic...

Determination of sialic acids in milks and milk-based products.

Anal. Biochem. 405(1) , 28-40, (2010)

Sialic acids are becoming recognized as important components of milk-based products for infants and young children. As such, many companies now label the sialic acid content of their products. To cont...

Production of monoclonal antibodies directed to Hanganutziu-Deicher active gangliosides, N-glycolylneuraminic acid-containing gangliosides.

J. Biochem. 117(5) , 1062-9, (1995)

We have established three kinds of monoclonal antibodies against gangliosides containing N-glycolylneuraminic acid (NeuGc) by immunization of BALB/c mice with the purified gangliosides inserted into l...

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