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月桂醇

月桂醇用途

1-Dodecanol 是一种内源性代谢产物。

月桂醇名称

[ CAS 号 ]:
112-53-8

[ 中文名 ]:
十二醇

[ 英文名 ]:
1-Dodecanol

[中文别名 ]:

[英文别名 ]:

1-Hydroxydodecane
Lauryl Alcohol
1-Dodecyl alcohol
n-Dodecanol
Alcohol C12,Dodecyl alcohol,Lauryl alcohol
Dodecyl alcohol
Hydroxydodecane
n-Lauryl alcohol
1-Dodecanol
EINECS 203-982-0

月桂醇生物活性

[ 描述 ]:

1-Dodecanol 是一种内源性代谢产物。

[ 相关类别 ]:

研究领域 >> 代谢疾病

[ 靶点 ]

Human Endogenous Metabolite

月桂醇物理化学性质

[ 密度 ]:
0.8±0.1 g/cm3

[ 沸点 ]:
258.0±3.0 °C at 760 mmHg

[ 熔点 ]:
22-26 °C(lit.)

[ 分子式 ]:
C₁₂H₂₆O

[ 分子量 ]:
186.334

[ 闪点 ]:
115.4±4.6 °C

[ 精确质量 ]:
186.198364

[ PSA ]:
20.23000

[ LogP ]:
5.13

[ 外观性状 ]:
无色液体在室温中

[ 蒸汽密度 ]:
7.4 (vs air)

[ 蒸汽压 ]:
0.0±1.2 mmHg at 25°C

[ 折射率 ]:
1.441

[ 储存条件 ]:
库房通风低温干燥

[ 水溶解性 ]:
insoluble

月桂醇MSDS

月桂醇毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: JR5775000

CHEMICAL NAME :: Dodecyl alcohol

CAS REGISTRY NUMBER :: 112-53-8

BEILSTEIN REFERENCE NO. :: 1738860

LAST UPDATED :: 199712

DATA ITEMS CITED :: 11

MOLECULAR FORMULA :: C12-H26-O

MOLECULAR WEIGHT :: 186.38

WISWESSER LINE NOTATION :: Q12

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Human

REFERENCE :: 85DKA8 "Cutaneous Toxicity, Proceedings of the 3rd Conference, 1976," Drill, V.A., and P. Lazar, eds., New York, Academic Press, Inc. 1977 Volume(issue)/page/year: -,127,1977 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >12800 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: MDZEAK Medizin und Ernaehrung. (Stuttgart, Fed. Rep. Ger.) V.1-13, 1959-72. Discontinued. Volume(issue)/page/year: 8,244,1967

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: >10 mL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 11,95,1973 ** TUMORIGENIC DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 19 gm/kg/39W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 9,70,1966 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 10 mg/m3;Skin JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 28510 No. of Facilities: 1027 (estimated) No. of Industries: 28 No. of Occupations: 40 No. of Employees: 28625 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 28510 No. of Facilities: 4159 (estimated) No. of Industries: 40 No. of Occupations: 50 No. of Employees: 58100 (estimated) No. of Female Employees: 20007 (estimated)

月桂醇安全信息

[ 符号 ]:

GHS07, GHS09

[ 信号词 ]:
Warning

[ 危害声明 ]:
H319-H410

[ 警示性声明 ]:
P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ 危害码 (欧洲) ]:
Xi:Irritant

[ 风险声明 (欧洲) ]:
R36/38;R50/53

[ 安全声明 (欧洲) ]:
S61-S37/39-S29-S26-S60-S36

[ 危险品运输编码 ]:
UN 3077 9/PG 3

[ WGK德国 ]:
1

[ RTECS号 ]:
JR5775000

[ 包装等级 ]:
III

[ 危险类别 ]:
9

[ 海关编码 ]:
2905170000

月桂醇合成路线

月桂醇上下游产品

月桂醇上游产品

月桂醇下游产品

月桂醇制备

1、高压加氢法　椰子油在铜铬催化剂中连续加氢，得到C8-C18的混合醇。油脂中的甘油则氢解为异丙醇和水。混合脂肪醇经常压蒸去水分及异丙醇后，减压蒸馏切割C8-C10醇、C12-C14醇和C16-C18醇。

2、酯化加氢法　椰子油在硫酸存在下与甲醇发生酯交换反应，生成月桂酸甲酯和甘油，经催化加氢、蒸馏，得月桂醇。

月桂醇海关

[ 海关编码 ]: 2905170000

[ 中文概述 ]:
2905170000 十二醇、十六醇及十八醇。监管条件:无。增值税率:17.0%。退税率:9.0%。最低关税:7.0%。普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 包装

[ Summary ]:
2905170000 hexadecan-1-ol。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。Lowest tariff:7.0%。General tariff:30.0%

月桂醇文献

Antioxidant activity of protocatechuates evaluated by DPPH, ORAC, and CAT methods.

Food Chem. 194 , 749-57, (2015)

Hibiscus sabdariffa L. is a worldwide consumed plant, principally after infusion of its dried sepals and calyces, which are usually discarded. Nevertheless, they represent a potential source of natura...

Vortex-assisted low density solvent liquid-liquid microextraction and salt-induced demulsification coupled to high performance liquid chromatography for the determination of five organophosphorus pesticide residues in fruits.

Talanta 132 , 769-74, (2014)

A simple and rapid microextraction method, vortex-assisted low density solvent liquid-liquid microextraction and salt-induced demulsification (VLLME-SID) coupled to high performance liquid chromatogra...

Evaluation of injection methods for fast, high peak capacity separations with low thermal mass gas chromatography.

J. Chromatogr. A. 1392 , 82-90, (2015)

Low thermal mass gas chromatography (LTM-GC) was evaluated for rapid, high peak capacity separations with three injection methods: liquid, headspace solid phase micro-extraction (HS-SPME), and direct ...

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月桂醇