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伊班膦酸

伊班膦酸用途

Ibandronic acid是高效含氮双磷酸盐,可作用于骨质疏松。

伊班膦酸名称

[ CAS 号 ]:
114084-78-5

[ 中文名 ]:
伊班膦酸

[ 英文名 ]:
ibandronic acid

[中文别名 ]:

伊班磷酸

[英文别名 ]:

Bondronat
ibandronic acid
Ibandronic acid [BAN:INN]

伊班膦酸生物活性

[ 描述 ]:

Ibandronic acid是高效含氮双磷酸盐,可作用于骨质疏松。

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

研究领域 >> 其他

[参考文献]

[1]. Morgan, C., S. Jeremiah, and J. Wagstaff, Metronomic administration of ibandronate and its anti-angiogenic effects in vitro. Microvasc Res, 2009. 78(3): p. 453-8.

[2]. Epplen, R., et al., Differential effects of ibandronate, docetaxel and farnesol treatment alone and in combination on the growth of prostate cancer cell lines. Acta Oncol, 2011. 50(1): p. 127-33.

[3]. Chesnut, I.C., et al., Effects of oral ibandronate administered daily or intermittently on fracture risk in postmenopausal osteoporosis. J Bone Miner Res, 2004. 19(8): p. 1241-9.

[4]. Bauss, F., et al., Effects of treatment with ibandronate on bone mass, architecture, biomechanical properties, and bone concentration of ibandronate in ovariectomized aged rats. J Rheumatol, 2002. 29(10): p. 2200-8.

[相关活性小分子]

伊班膦酸物理化学性质

[ 密度 ]:
1.5±0.1 g/cm3

[ 沸点 ]:
587.8±60.0 °C at 760 mmHg

[ 熔点 ]:
113-115ºC

[ 分子式 ]:
C₉H₂₃NO₇P₂

[ 分子量 ]:
319.229

[ 闪点 ]:
309.3±32.9 °C

[ 精确质量 ]:
319.094971

[ PSA ]:
158.15000

[ LogP ]:
-0.65

[ 外观性状 ]:
白色半固体

[ 蒸汽压 ]:
0.0±3.7 mmHg at 25°C

[ 折射率 ]:
1.538

[ 储存条件 ]:
-20°C Freezer

伊班膦酸安全信息

[ 海关编码 ]:
2931900090

伊班膦酸合成路线

详细合成路线

伊班膦酸上下游产品

伊班膦酸上游产品

伊班膦酸下游产品

伊班膦酸海关

[ 海关编码 ]: 2931900090

[ 中文概述 ]:
2931900090. 其他有机-无机化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:AB(入境货物通关单,出境货物通关单). 最惠国关税:6.5%. 普通关税:30.0%

[ Summary ]:
2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0%