<生产厂家 价格>

arg-pro-pro-gly-phe-ser-pro-leu acetate salt

用途

Des-Arg9-[Leu8]-Bradykinin acetate 是有效的 缓激肽受体1 (B1R) 拮抗剂。Des-Arg9-[Leu8]-Bradykinin acetate 可用于肾纤维化研究。

名称

[ CAS 号 ]:
115035-45-5

[ 英文名 ]:
arg-pro-pro-gly-phe-ser-pro-leu acetate salt

[英文别名 ]:

生物活性

[ 描述 ]:

Des-Arg9-[Leu8]-Bradykinin acetate 是有效的 缓激肽受体1 (B1R) 拮抗剂。Des-Arg9-[Leu8]-Bradykinin acetate 可用于肾纤维化研究。

[ 相关类别 ]:

研究领域 >> 炎症/免疫
信号通路 >> G 蛋白偶联受体/G 蛋白 >> 缓激肽受体

[ 靶点 ]

IC50: B1R[1]


[参考文献]

[1]. Ji-Zhe Jin, et al. Exogenous pancreatic kininogenase protects against renal fibrosis in rat model of unilateral ureteral obstruction. Acta Pharmacol Sin. 2020 Dec;41(12):1597-1608.  

物理化学性质

[ 分子式 ]:
C43H67N11O12

[ 分子量 ]:
930.06

[ 精确质量 ]:
929.49700

[ PSA ]:
360.08000

[ LogP ]:
0.84570

安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

文献

Upregulation of B1 receptor mediating des-Arg9-BK-induced rat paw oedema by systemic treatment with bacterial endotoxin.

Br. J. Pharmacol. 117 , 793-798, (1996)

1. The effect of pretreatment with bacterial endotoxin (LPS, 10 micrograms, i.v., 24 h) on the bradykinin B1 and B2 receptor-induced oedema in the rat paw, and the interaction of B1-mediated responses...

Angiotensin II type 2 receptor expression after vascular injury: differing effects of angiotensin-converting enzyme inhibition and angiotensin receptor blockade.

Hypertension 48 , 942-949, (2006)

It has been suggested that the effects of angiotensin II type 1 receptor (AT1R) blockers are in part because of angiotensin II type 2 receptor (AT2R) signaling. Interactions between the AT2R and kinin...

The role of kinin B1 receptors in the nociception produced by peripheral protein kinase C activation in mice.

Neuropharmacology 54 , 597-604, (2008)

The peripheral injection of phorbol myristate acetate (PMA) into the mouse paw induces nociception mediated through activation of protein kinase C (PKC). In the present study, we examine the contribut...


更多文献

推荐生产厂家/供应商:

公司名:上海化源世纪贸易有限公司

区域:上海市普陀区

价格:

联系人:徐乾明

产品详情:des-Arg?-[Leu?]-缓激肽醋酸盐


公司名:南京肽业生物科技有限公司

区域:南京市六合区

价格:
¥需询单/10g ¥需询单/100g ¥需询单/1kg ¥需询单/10kg

联系人:滕经理

产品详情:arg-pro-pro-gly-phe-ser-pro-leu acetate salt


查看所有供应商请点击:

arg-pro-pro-gly-phe-ser-pro-leu acetate salt供应商


相关化合物

CAS号[115035-45-5]化源网提供[arg-pro-pro-gly-phe-ser-pro-leu acetate salt]MSDS、说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。>>电脑版:arg-pro-pro-gly-phe-ser-pro-leu acetate salt

标题:【arg-pro-pro-gly-phe-ser-pro-leu acetate salt】arg-pro-pro-gly-phe-ser-pro-leu acetate salt CAS号:115035-45-5【结构式 性质 活性】-化源网 地址:https://www.chemsrc.com/amp/cas/115035-45-5_47658.html