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3,5-二硝基苯甲酰胺

3,5-二硝基苯甲酰胺用途

Nitromide是一种抗寄生虫药。

3,5-二硝基苯甲酰胺名称

[ CAS 号 ]:
121-81-3

[ 中文名 ]:
3,5-二硝基苯甲酰胺

[ 英文名 ]:
Nitromide

[中文别名 ]:

硝米特

[英文别名 ]:

Benzamide,3,5-dinitro
Unistat
MFCD00007985
3,5-dinitro-benzoic acid amide
EINECS 204-499-8
component of Tristat
Nitroamide
component of Unistat-3
Tristat
3,5-Dinitro-benzoesaeure-amid

3,5-二硝基苯甲酰胺生物活性

[ 描述 ]:

Nitromide是一种抗寄生虫药。

[ 相关类别 ]:

信号通路 >> 抗感染 >> 寄生物

研究领域 >> 感染

[相关活性小分子]

3,5-二硝基苯甲酰胺物理化学性质

[ 密度 ]:
1.601g/cm3

[ 沸点 ]:
314.5ºC at 760mmHg

[ 熔点 ]:
183-185 °C(lit.)

[ 分子式 ]:
C₇H₅N₃O₅

[ 分子量 ]:
211.13200

[ 闪点 ]:
144ºC

[ 精确质量 ]:
211.02300

[ PSA ]:
134.73000

[ LogP ]:
2.34860

[ 外观性状 ]:
淡黄色粉末

[ 蒸汽压 ]:
0.000466mmHg at 25°C

[ 折射率 ]:
1.653

[ 储存条件 ]:
2-8℃

3,5-二硝基苯甲酰胺MSDS

3,5-二硝基苯甲酰胺毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CV4752300

CHEMICAL NAME :: Benzamide, 3,5-dinitro-

CAS REGISTRY NUMBER :: 121-81-3

BEILSTEIN REFERENCE NO. :: 1981935

LAST UPDATED :: 199612

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C7-H5-N3-O5

MOLECULAR WEIGHT :: 211.15

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1250 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 7,488,1965

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 320 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 7,488,1965

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - chicken

DOSE/DURATION :: 900 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 7,488,1965

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Bird - chicken

DOSE/DURATION :: 280 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 7,488,1965

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - turkey

DOSE/DURATION :: 1150 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 7,488,1965

3,5-二硝基苯甲酰胺安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xn:Harmful;

[ 风险声明 (欧洲) ]:
R22

[ 安全声明 (欧洲) ]:
S26-S36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
CV4752300

[ 海关编码 ]:
2924299090

3,5-二硝基苯甲酰胺合成路线

3,5-二硝基苯甲酰胺上下游产品

3,5-二硝基苯甲酰胺上游产品

3,5-二硝基苯甲酰胺下游产品

3,5-二硝基苯甲酰胺制备

一、生产方法简介

用3,5-二硝基苯酰氯与醋酸铵反应制得。

3,5-二硝基苯甲酰胺海关

[ 海关编码 ]: 2924299090

[ 中文概述 ]:
2924299090. 其他环酰胺（包括环氨基甲酸酯）（包括其衍生物以及他们的盐）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 包装

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

3,5-二硝基苯甲酰胺文献

Highly sensitive voltammetric sensor based on catechol-derivative-multiwall carbon nanotubes for the catalytic determination of captopril in patient human urine samples.

Colloids Surf. B Biointerfaces 87(2) , 480-8, (2011)

A new catechol-derivative compound, N-(3,4-dihydroxyphenethyl)-3,5-dinitrobenzamide, was synthesized and used to construct a modified-carbon nanotubes paste electrode. The electro-oxidation of captopr...

Preparative enantioseparation of (+/-)-N-(3,4-cis-3-decyl-1,2,3,4-tetrahydrophenanthren-4-yl)-3,5-dinitrobenzamide by centrifugal partition chromatography.

J. Chromatogr. A. 1217(8) , 1183-90, (2010)

The racemic compound (+/-)-N-(3,4-cis-3-decyl-1,2,3,4-tetrahydrophenanthren-4-yl)-3,5-dinitrobenzamide ((+/-)-1), an analogue of increased lipophilicity of the chiral selector (CS) contained in the Wh...

Metabolism of nitromide in the rat. II. Sites of nitro-reduction.

Xenobiotica 10(4) , 299-305, (1980)

1. Nitromide (3,5-dinitrobenzamide) is reduced to monoamino- and diamino-metabolites in vitro on anaerobic incubation with rat intestinal microflora. This conversion is suppressed by the antibiotics n...

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