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硫代二丙酸双十二烷酯

硫代二丙酸双十二烷酯用途

硫代二丙酸二月桂酯是一种生物化学试剂,可作为生物材料或有机化合物用于生命科学相关研究。

硫代二丙酸双十二烷酯名称

[ CAS 号 ]:
123-28-4

[ 中文名 ]:
硫代二丙酸双十二烷酯

[ 英文名 ]:
Dilauryl 3,3'-thiodipropionate

[中文别名 ]:

[英文别名 ]:

Dilauryl thiodipropionate
3,3'-Thiodipropionic acid dilauryl ester
DMPTP
didodecyl 3,3'-thiodipropanoate
DLTP
dilaurylthiodipropionate
Cyanox LTDP
3,3'-Thiodipropionic Acid Didodecyl Ester
DLT
Dilaurylthiopropionate

硫代二丙酸双十二烷酯生物活性

[ 描述 ]:

硫代二丙酸二月桂酯是一种生物化学试剂,可作为生物材料或有机化合物用于生命科学相关研究。

[ 相关类别 ]:

研究领域 >> 其他

硫代二丙酸双十二烷酯物理化学性质

[ 密度 ]:
0.9±0.1 g/cm3

[ 沸点 ]:
580.8±35.0 °C at 760 mmHg

[ 熔点 ]:
40-42 °C(lit.)

[ 分子式 ]:
C₃₀H₅₈O₄S

[ 分子量 ]:
514.844

[ 闪点 ]:
264.8±14.0 °C

[ 精确质量 ]:
514.405579

[ PSA ]:
77.90000

[ LogP ]:
12.88

[ 外观性状 ]:
白色结晶粉末

[ 蒸汽压 ]:
0.0±1.6 mmHg at 25°C

[ 折射率 ]:
1.472

[ 储存条件 ]:
室温，密封

硫代二丙酸双十二烷酯MSDS

硫代二丙酸双十二烷酯毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UF8000000

CHEMICAL NAME :: Propionic acid, 3,3'-thiodi-, didodecyl ester

CAS REGISTRY NUMBER :: 123-28-4

BEILSTEIN REFERENCE NO. :: 1808848

LAST UPDATED :: 199701

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C30-H58-O4-S

MOLECULAR WEIGHT :: 514.94

WISWESSER LINE NOTATION :: 12OV2S2VO12

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,1007,1986 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >2500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AFREAW Advances in Food Research. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1-32, 1948-88. Volume(issue)/page/year: 3,197,1951

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 11,25,1992

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 11,25,1992

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Mammal - species unspecified

DOSE/DURATION :: >15 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 42(7),74,1977 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X3881 No. of Facilities: 1282 (estimated) No. of Industries: 15 No. of Occupations: 21 No. of Employees: 18006 (estimated) No. of Female Employees: 7083 (estimated)

硫代二丙酸双十二烷酯安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xi:Irritant;

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
1

[ RTECS号 ]:
UF8000000

[ 海关编码 ]:
2930909090

硫代二丙酸双十二烷酯合成路线

硫代二丙酸双十二烷酯上下游产品

硫代二丙酸双十二烷酯上游产品

硫代二丙酸双十二烷酯下游产品

硫代二丙酸双十二烷酯制备

1. 丙烯腈路线
丙烯腈与硫化钠水溶液在20'E：±2℃下缩合，反应产物经水洗、分离，再用55%的硫酸水解得到硫代二丙酸；将析出并分离得到的硫代二丙酸溶于水中，在硫酸作用下，与月桂醇减压酯化，反应产物经丙酮溶解、碳酸钠中和、压滤、结晶、过滤、干燥得成品。
每吨产品消耗丙烯腈700kg，57%的硫化钠900kg，浓硫酸700kg，月桂醇1100kg。
2CH2＝CHCN+Na2S→S(CH＝CHCOONa)2[H2SO4] →S(CH＝CHCOOH)2
S(CH＝CHCOOH)2+2C12H25OH→S(CH＝CHCOOC12H25)2+2H2O

硫代二丙腈的制备　将丙烯腈加入搅拌反应器中，搅拌下缓缓加入硫化钠水溶液，在（20±2）℃下进行缩合反应，反应产物经水洗、分离，得硫代二丙腈：

2. 丙烯酸路线
在50℃含NaOH的Na2S水溶液中滴加定量的丙烯酸，控制滴加速度使温度低于75℃，滴加完毕后，加热至沸，回流1.5h。待溶液稍冷后，加人50%的硫酸至Ph=1，冷却后析出硫代二丙酸，过滤得粗品，熔点为26℃。
在上述产品中加入定量的月桂醇，在真空下缓缓加热至硫代二丙酸全部溶解，反应终点温度为110℃，真空度大于0.097MPa，然后向混合物中加入水，使产物析出；先后用碳酸钠溶液和水洗至中性，经真空干燥得成品，熔点39～40℃。
2CH2＝CHCOOH+Na2S→S(CH＝CHCOONa)2[H2SO4] →S(CH＝CHCOOH)2
S(CH＝CHCOOH)2+2C12H25OH→S(CH＝CHCOOC12H25)2+2H2O

硫代二丙酸的制备　将硫代二丙腈加入搪玻璃反应釜，搅拌下加入55%的硫酸溶液进行水解，反应产物经过滤得硫代二丙酸：

抗氧剂TPL的制备　将硫代二丙酸和水加入搪玻璃反应釜，搅拌溶解后，加入月桂醇和浓硫酸，搅拌下进行酯化反应，得粗品抗氧剂DLTP。酯化反应在负压下操作，脱除反应生成的水。反应产物经丙酮溶解、碳酸钠中和、压滤、结晶、过滤、干燥而得成品。反应式如下：

硫代二丙酸双十二烷酯海关

[ 海关编码 ]: 2930909090

[ 中文概述 ]:
2930909090. 其他有机硫化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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