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N,N-二羟乙基甘氨酸

N,N-二羟乙基甘氨酸用途

比辛在生理学意义上是一种有用的缓冲剂。比辛是简单氨基酸甘氨酸的衍生物。

N,N-二羟乙基甘氨酸名称

[ CAS 号 ]:
150-25-4

[ 中文名 ]:
N,N-二羟乙基甘氨酸

[ 英文名 ]:
N,N-bis(2-hydroxyethyl)glycine

[中文别名 ]:

[英文别名 ]:

Diethylolglycine
Di(hydroxyethyl)glycine
Glycine, N, N-dihydroxyethyl-
N,N-Dihydroxyethyl glycine
bicine buffer
Bis(2-Hydroxyethyl)glycine
Bicine
BICINE[N,N-Di(2-hydroxyethyl)glycine]
EINECS 205-755-1
Bicene

N,N-二羟乙基甘氨酸生物活性

[ 描述 ]:

比辛在生理学意义上是一种有用的缓冲剂。比辛是简单氨基酸甘氨酸的衍生物。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[参考文献]

[1]. Taha M, et al. Mixed-ligand complex formation equilibria of cobalt (II), nickel (II), and copper (II) with N, N-bis (2-hydroxyethyl) glycine (bicine) and some amino acids[J]. Journal of Chemical & Engineering Data, 2005, 50(1): 157-163.

N,N-二羟乙基甘氨酸物理化学性质

[ 密度 ]:
1.3±0.1 g/cm3

[ 沸点 ]:
388.5±27.0 °C at 760 mmHg

[ 熔点 ]:
190 °C (dec.)(lit.)

[ 分子式 ]:
C₆H₁₃NO₄

[ 分子量 ]:
163.17

[ 闪点 ]:
188.8±23.7 °C

[ 精确质量 ]:
163.084457

[ PSA ]:
81.00000

[ LogP ]:
-0.47

[ 外观性状 ]:
白色结晶粉末

[ 蒸汽压 ]:
0.0±2.0 mmHg at 25°C

[ 折射率 ]:
1.526

[ 储存条件 ]:
2-8°C

[ 水溶解性 ]:
soluble

N,N-二羟乙基甘氨酸MSDS

N,N-二羟乙基甘氨酸毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MB9700000

CHEMICAL NAME :: Glycine, N,N-dihydroxyethyl-

CAS REGISTRY NUMBER :: 150-25-4

BEILSTEIN REFERENCE NO. :: 1769362

LAST UPDATED :: 199701

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C6-H13-N-O4

MOLECULAR WEIGHT :: 163.20

WISWESSER LINE NOTATION :: QV1N2Q2Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1540 mg/kg

TOXIC EFFECTS :: Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis)

REFERENCE :: REPMBN Revue d'Epidemiologie, Medecine Sociale et Sante Publique. (Masson Editeur, 120 Blvd. Saint-Germain, F-75280 Paris Cedex O6, France) V.1- 1953- Volume(issue)/page/year: 10,391,1962 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X9723 No. of Facilities: 130 (estimated) No. of Industries: 1 No. of Occupations: 3 No. of Employees: 1828 (estimated) No. of Female Employees: 1552 (estimated)

N,N-二羟乙基甘氨酸安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xn

[ 风险声明 (欧洲) ]:
R20/21/22

[ 安全声明 (欧洲) ]:
S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
MB9700000

[ 海关编码 ]:
29225000

N,N-二羟乙基甘氨酸合成路线

N,N-二羟乙基甘氨酸上下游产品

N,N-二羟乙基甘氨酸上游产品

N,N-二羟乙基甘氨酸下游产品

N,N-二羟乙基甘氨酸海关

[ 海关编码 ]: 29225000

N,N-二羟乙基甘氨酸文献

Endothelial transcriptome in response to pharmacological methyltransferase inhibition.

ChemMedChem 9(8) , 1755-62, (2014)

The enzymatic activities of protein methyltransferases serve to write covalent modifications on histone and non-histone proteins in the control of gene transcription. Here, we describe gene expression...

A Comprehensive Immunoreceptor Phosphotyrosine-based Signaling Network Revealed by Reciprocal Protein-Peptide Array Screening.

Mol. Cell. Proteomics 14 , 1846-58, (2015)

Cells of the immune system communicate with their environment through immunoreceptors. These receptors often harbor intracellular tyrosine residues, which, when phosphorylated upon receptor activation...

Solubilization of gliadins for use as a source of nitrogen in the selection of bacteria with gliadinase activity.

Food Chem. 168 , 439-44, (2014)

For patients with celiac disease, gliadin detoxification via the use of gliadinases may provide an alternative to a gluten-free diet. A culture medium, in which gliadins were the sole source of nitrog...

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