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杀螟丹

杀螟丹用途

Cartap hydrochloride 是一种有机氮杀虫剂,可在离体的小鼠和兔神经膜片中引起明显的不可逆的 Ca2+ 依赖性挛缩。Cartap hydrochloride 显着增了 C2C12 细胞中内源性活性氧 (ROS) 的水平。

杀螟丹名称

[ CAS 号 ]:
15263-52-2

[ 中文名 ]:
杀螟丹盐酸盐

[ 英文名 ]:
Cartap Hydrochloride

[中文别名 ]:

[英文别名 ]:

vegetox
UNII-IWO0R06728
kartap
Cartapp
ntd2
Cartap hydrochloride
patap
Cadan
Cartap monohydrochloride
EINECS 239-309-2

杀螟丹生物活性

[ 描述 ]:

[ 相关类别 ]:

研究领域 >> 感染

[参考文献]

[1]. Jiunn-Wang Liao, et al. Cartap-induced cytotoxicity in mouse C2C12 myoblast cell line and the roles of calcium ion and oxidative stress on the toxic effects. Toxicology. 2006 Feb 15;219(1-3):73-84

杀螟丹物理化学性质

[ 密度 ]:
1.42 g/cm3 (20ºC)

[ 沸点 ]:
407.2ºC at 760 mmHg

[ 熔点 ]:
54-58 °C(lit.)

[ 分子式 ]:
C₇H₁₆ClN₃O₂S₂

[ 分子量 ]:
273.804

[ 闪点 ]:
200.1ºC

[ 精确质量 ]:
273.037231

[ PSA ]:
140.02000

[ LogP ]:
2.74300

[ 外观性状 ]:
固体

[ 蒸汽压 ]:
7.7E-07mmHg at 25°C

[ 储存条件 ]:
库房通风低温干燥,与食品原料分开储运

杀螟丹MSDS

详细MSDS(安全技术说明书)

杀螟丹毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: FD1225000

CHEMICAL NAME :: Carbamic acid, thio-, S,S'-(2-(dimethylamino)trimethylene) ester, monohydrochloride

CAS REGISTRY NUMBER :: 15263-52-2

LAST UPDATED :: 199707

DATA ITEMS CITED :: 8

MOLECULAR FORMULA :: C7-H15-N3-O2-S2.Cl-H

MOLECULAR WEIGHT :: 273.83

WISWESSER LINE NOTATION :: ZVS1Y1SVZN1&1 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 250 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ABCHA6 Agricultural and Biological Chemistry. (Maruzen Co. Ltd., POB 5050, Tokyo International, Tokyo 100-31, Japan) V.25- 1961- Volume(issue)/page/year: 34,935,1970

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 165 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 1,78,1967

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,132,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 59 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - respiratory depression

REFERENCE :: JJPAAZ Japanese Journal of Pharmacology. (Japanese Pharmacological Soc., c/o Dept. of Pharmacology, Faculty of Medicine, Kyoto Univ., Sakyo-ku, Kyoto 606, Japan) V.1- 1951- Volume(issue)/page/year: 17,491,1967

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - species unspecified

DOSE/DURATION :: 390 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: HPBIA9 Herba Polonica. (Ars Polona, POB 1001, 00-068 Warsaw 1, Poland) V.11- 1965- Volume(issue)/page/year: 21,53,1975 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 700 mg/kg

SEX/DURATION :: female 9-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - musculoskeletal system

REFERENCE :: TAKHAA Takeda Kenkyusho Ho. Journal of the Takeda Research Laboratories. (Takeda Yakuhin Kogyo K.K., 2-17-85 Jusohon-machi, Yodogawa-ku, Osaka 532, Japan) V.29- 1970- Volume(issue)/page/year: 30,776,1971

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 300 mg/kg

SEX/DURATION :: female 8-13 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - musculoskeletal system

REFERENCE :: TAKHAA Takeda Kenkyusho Ho. Journal of the Takeda Research Laboratories. (Takeda Yakuhin Kogyo K.K., 2-17-85 Jusohon-machi, Yodogawa-ku, Osaka 532, Japan) V.29- 1970- Volume(issue)/page/year: 30,776,1971

杀螟丹安全信息

[ 符号 ]:

GHS07, GHS09

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302-H312-H410

[ 警示性声明 ]:
P273-P280-P501

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ 危害码 (欧洲) ]:
Xn:Harmful;N:Dangerousfortheenvironment;

[ 风险声明 (欧洲) ]:
R21/22;R50/53

[ 安全声明 (欧洲) ]:
2-36/37-60-61

[ 危险品运输编码 ]:
2771

[ WGK德国 ]:
3

[ RTECS号 ]:
FD1225000

[ 包装等级 ]:
III

[ 危险类别 ]:
6.1(b)

[ 海关编码 ]:
2930200011

杀螟丹海关

[ 海关编码 ]: 2930200011

[ 中文概述 ]:
2930200011 禾草丹、杀螟丹。监管条件:S(进出口农药登记证明)。增值税率:17.0%。退税率:9.0%。最低关税:6.5%。普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ 监管条件 ]: S.进出口农药登记证明

[ Summary ]:
2930200011 s,s'-(2-(dimethylamino)propane-1,3-diyl) dicarbamothioate。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:30.0%

杀螟丹文献

Effects of various insecticides on the development of the egg parasitoid Trichogramma dendrolimi (Hymenoptera: Trichogrammatidae).

J. Econ. Entomol. 94(6) , 1340-3, (2001)

The toxicity of six insecticides, acephate, methomyl, ethofenprox, cartap, chlorfluazuron, and Bacillus thuringiensis (Bt) was tested on different developmental stages of the egg parasitoid, Trichogra...

Microbial biomass and carbon mineralization in agricultural soils as affected by pesticide addition.

Bull. Environ. Contam. Toxicol. 88(4) , 538-42, (2012)

A laboratory study was conducted with four pesticides, viz. a fungicide (carbendazim), two insecticides (chlorpyrifos and cartap hydrochloride) and an herbicide (pretilachlor) applied to a sandy clay ...

Assessment of the molluscicidal activities of Tribromosalan, Cartap and Chlorothalonil against Oncomelania hupensis.

Jpn. J. Med. Sci. Biol. 45(2) , 75-80, (1992)

Molluscicidal activities of Tribromosalan, Cartap and Chlorothalonil were evaluated in the laboratory and the field against Oncomelania hupensis, the intermediate host of Schistosoma japonicum in Chin...

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杀螟丹