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杀螟丹

杀螟丹用途

Cartap 是一种有机氮杀虫剂,可在离体的小鼠和兔神经膜片中引起明显的不可逆的 Ca2+ 依赖性挛缩。

杀螟丹名称

[ CAS 号 ]:
15263-53-3

[ 中文名 ]:
杀螟丹

[ 英文名 ]:
Cartap

[中文别名 ]:

杀虫双

[英文别名 ]:

Patap
thiobel
Dihydronereistoxin dicarbamate
Cartap
sanvex
TL-1258
UNII-Z45YUY784H
Vegetox
SS2DIMETHYLAMINO13PROPANEDIYLDITHIOCARBAMATE
t-1258

杀螟丹生物活性

[ 描述 ]:

Cartap 是一种有机氮杀虫剂,可在离体的小鼠和兔神经膜片中引起明显的不可逆的 Ca2+ 依赖性挛缩。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[体外研究]

Cartap(10-1000μM；24小时)对C2C12细胞具有剂量和时间依赖性的细胞毒性作用。Cartap显著增加C2C12细胞内源性活性氧(ROS)水平,呈剂量和时间依赖性[1]。

[参考文献]

[1]. Jiunn-Wang Liao, et al. Cartap-induced cytotoxicity in mouse C2C12 myoblast cell line and the roles of calcium ion and oxidative stress on the toxic effects. Toxicology. 2006 Feb 15;219(1-3):73-84.

杀螟丹物理化学性质

[ 密度 ]:
1.3±0.1 g/cm3

[ 沸点 ]:
407.2±55.0 °C at 760 mmHg

[ 熔点 ]:
-80ºC

[ 分子式 ]:
C₇H₁₅N₃O₂S₂

[ 分子量 ]:
237.343

[ 闪点 ]:
200.1±31.5 °C

[ 精确质量 ]:
237.060562

[ PSA ]:
140.02000

[ LogP ]:
0.53

[ 外观性状 ]:
无色略吸湿的和结晶固体带有淡气味

[ 蒸汽压 ]:
0.0±0.9 mmHg at 25°C

[ 折射率 ]:
1.591

[ 储存条件 ]:
室温

[ 稳定性 ]:
Stable. Incompatible with strong oxidizing agents.

杀螟丹毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: FD1220000

CHEMICAL NAME :: Carbamic acid, thio-, S,S'-(2-(dimethylamino)trimethylene) ester

CAS REGISTRY NUMBER :: 15263-53-3

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C7-H15-N3-O2-S2

MOLECULAR WEIGHT :: 237.37

WISWESSER LINE NOTATION :: ZVS1Y1SVZN1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 225 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EVHPAZ EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents, Washington, DC 20402) No.1- 1972- Volume(issue)/page/year: 14,109,1976

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 92 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ABCHA6 Agricultural and Biological Chemistry. (Maruzen Co. Ltd., POB 5050, Tokyo International, Tokyo 100-31, Japan) V.25- 1961- Volume(issue)/page/year: 34,935,1970

杀螟丹安全信息

[ 危害码 (欧洲) ]:
N: Dangerous for the environment;

[ 风险声明 (欧洲) ]:
R50/53

[ 安全声明 (欧洲) ]:
60-61

[ 海关编码 ]:
2930909054

杀螟丹海关

[ 海关编码 ]: 2930200011

[ 中文概述 ]:
2930200011 禾草丹、杀螟丹。监管条件:S(进出口农药登记证明)。增值税率:17.0%。退税率:9.0%。最低关税:6.5%。普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ 监管条件 ]: S.进出口农药登记证明

[ Summary ]:
2930200011 s,s'-(2-(dimethylamino)propane-1,3-diyl) dicarbamothioate。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:30.0%

杀螟丹