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3-氨基-5-苯基吡唑

3-氨基-5-苯基吡唑用途

5-苯基-1H-吡唑-3-胺是一种生物化学试剂,可作为生物材料或有机化合物用于生命科学相关研究。

3-氨基-5-苯基吡唑名称

[ CAS 号 ]:
1572-10-7

[ 中文名 ]:
3-氨基-5-苯基吡唑

[ 英文名 ]:
3-Phenyl-1H-pyrazol-5-amine

[中文别名 ]:

5-氨基-3-苯基吡唑

[英文别名 ]:

MFCD00191749
1H-Pyrazol-3-amine, 5-phenyl-
1H-Pyrazol-5-amine, 3-phenyl-
3-Phenyl-1H-pyrazol-5-amine
3-Amino-5-phenylpyrazole

3-氨基-5-苯基吡唑生物活性

[ 描述 ]:

5-苯基-1H-吡唑-3-胺是一种生物化学试剂,可作为生物材料或有机化合物用于生命科学相关研究。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

3-氨基-5-苯基吡唑物理化学性质

[ 密度 ]:
1.2±0.1 g/cm3

[ 沸点 ]:
442.3±33.0 °C at 760 mmHg

[ 熔点 ]:
118-121ºC

[ 分子式 ]:
C₉H₉N₃

[ 分子量 ]:
159.19

[ 闪点 ]:
251.5±12.6 °C

[ 精确质量 ]:
159.079651

[ PSA ]:
54.70000

[ LogP ]:
1.34

[ 外观性状 ]:
棕色固体

[ 蒸汽压 ]:
0.0±1.1 mmHg at 25°C

[ 折射率 ]:
1.663

[ 储存条件 ]:
存放于惰性气体之中;避免空气

3-氨基-5-苯基吡唑MSDS

详细MSDS(安全技术说明书)

3-氨基-5-苯基吡唑毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UQ6109000

CHEMICAL NAME :: Pyrazole, 5-amino-3-phenyl-

CAS REGISTRY NUMBER :: 1572-10-7

BEILSTEIN REFERENCE NO. :: 0004947

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C9-H9-N3

MOLECULAR WEIGHT :: 159.21

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 630 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 27,295,1964

3-氨基-5-苯基吡唑安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi:Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S37/39

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
UQ6109000

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3-氨基-5-苯基吡唑文献

Anthranilamide-pyrazolo[1,5-a]pyrimidine conjugates as p53 activators in cervical cancer cells.

ChemMedChem 7(8) , 1453-64, (2012)

A library of new anthranilamide-pyrazolo[1,5-a]pyrimidine conjugates were designed, synthesized, and evaluated for their anticancer activity in cervical cancer cells such as HeLa and SiHa that possess...

Botulinum neurotoxin serotype A inhibitors: small-molecule mercaptoacetamide analogs.

Bioorg. Med. Chem. 17(8) , 3072-9, (2009)

Botulinum neurotoxin elicits its paralytic activity through a zinc-dependant metalloprotease that cleaves proteins involved in neurotransmitter release. Currently, no drugs are available to reverse th...

An efficient one-step synthesis of heterobiaryl pyrazolo[3,4-b]pyridines via indole ring opening.

Org. Lett. 11(22) , 5214-7, (2009)

A mild one-step synthetic method to access privileged heterobiaryl pyrazolo[3,4-b]pyridines from indole-3-carboxaldehyde derivatives and a variety of aminopyrazoles has been developed. This novel meth...

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