L-1,4-二硫代苏糖醇
L-1,4-二硫代苏糖醇用途
L-1,4-二硫代苏糖醇名称
[ CAS 号 ]:
16096-97-2
[ 中文名 ]:
L-二硫苏糖醇
[ 英文名 ]:
1,4-Dithiothreitol
[中文别名 ]:
[英文别名 ]:
- Cleland reagent chiral
- 2,3-Butanediol, 1,4-dimercapto-, (2R,3R)-rel-
- (2R,3R)-1,4-Disulfanyl-2,3-butanediol
- 1,4-Dithiothreitol
- L-(−)-Dithiothreitol
- 1,4-Bissulfanylbutane-2,3-diol
- DL-1,4-Dimercapto-2,3-dihydroxybutane
- (2R,3R)-(-)-2,3-Dihydroxy-1,4-butanedithiol
- 1,4-Disulfanyl-2,3-butanediol
- (R*,R*)-1,4-DIMERCAPTO-2,3-BUTANEDIOL
L-1,4-二硫代苏糖醇生物活性
L-1,4-二硫代苏糖醇物理化学性质
[ 密度 ]:
1.3±0.1 g/cm3
[ 沸点 ]:
364.5±42.0 °C at 760 mmHg
[ 熔点 ]:
42-44ºC
[ 分子式 ]:
C4H10O2S2
[ 分子量 ]:
154.251
[ 闪点 ]:
174.2±27.9 °C
[ 精确质量 ]:
154.012222
[ PSA ]:
118.06000
[ LogP ]:
0.07
[ 外观性状 ]:
白色结晶粉末
[ 蒸汽压 ]:
0.0±1.8 mmHg at 25°C
[ 折射率 ]:
1.579
[ 储存条件 ]:
−20°C
L-1,4-二硫代苏糖醇MSDS
L-1,4-二硫代苏糖醇毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- EK1612000
- CHEMICAL NAME :
- 2,3-Butanediol, 1,4-dimercapto-, L-threo-
- CAS REGISTRY NUMBER :
- 16096-97-2
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C4-H10-O2-S2
- MOLECULAR WEIGHT :
- 154.26
- WISWESSER LINE NOTATION :
- SH1YQYQ1SH -L,THREO
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 179 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 15,600,1972
L-1,4-二硫代苏糖醇安全信息
[ 符号 ]:
GHS07
[ 信号词 ]:
Warning
[ 危害声明 ]:
H302-H312-H315-H319-H335
[ 警示性声明 ]:
P261-P280-P305 + P351 + P338
[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves
[ 危害码 (欧洲) ]:
Xn: Harmful;
[ 风险声明 (欧洲) ]:
R21/22
[ 安全声明 (欧洲) ]:
26-36/37
[ 危险品运输编码 ]:
UN 3335
[ WGK德国 ]:
3
[ RTECS号 ]:
EK1612000
[ 危险类别 ]:
9.0
[ 海关编码 ]:
2930909090
L-1,4-二硫代苏糖醇合成路线
L-1,4-二硫代苏糖醇上下游产品
L-1,4-二硫代苏糖醇上游产品
L-1,4-二硫代苏糖醇下游产品
L-1,4-二硫代苏糖醇海关
[ 海关编码 ]: 2930909090
[ 中文概述 ]:
2930909090. 其他有机硫化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
[ 申报要素 ]: 品名, 成分含量, 用途
[ Summary ]:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
L-1,4-二硫代苏糖醇文献
Cancer Prev. Res. (Phila.) 8(3) , 208-21, (2015)
Exposure to toxicants leads to cumulative molecular changes that overtime increase a subject's risk of developing urothelial carcinoma. To assess the impact of arsenic exposure at a time progressive m...
The mTOR inhibitor rapamycin synergizes with a fatty acid synthase inhibitor to induce cytotoxicity in ER/HER2-positive breast cancer cells.PLoS ONE 9(5) , e97697, (2014)
Patients with ER/HER2-positive breast cancer have a poor prognosis and are less responsive to selective estrogen receptor modulators; this is presumably due to the crosstalk between ER and HER2. Fatty...
Matrix stiffening and β1 integrin drive subtype-specific fibroblast accumulation in lung cancer.Mol. Cancer Res. 13(1) , 161-73, (2015)
The crucial role of tumor-associated fibroblasts (TAF) in cancer progression is now clear in non-small cell lung cancer (NSCLC). However, therapies against TAFs are limited due to a lack of understand...
推荐生产厂家/供应商:
公司名:上海化源世纪贸易有限公司
区域:上海市普陀区
价格:
联系人:徐经理
产品详情:L-二硫苏糖醇
公司名:上海吉至生化科技有限公司
区域:上海市奉贤区
价格:
¥2958.0/1g
¥9328.0/5g
联系人:刘佳
产品详情:L-二硫苏糖醇
公司名:上海阿拉丁生化科技股份有限公司
区域:上海市浦东新区
价格:
¥772.9/250mg
¥2162.9/1g
¥需询单/1g
¥需询单/1g
联系人:阿拉丁
产品详情:L-二硫苏糖醇
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相关化合物
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