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妊娠二醇3Α单葡萄糖醛酸苷

妊娠二醇3Α单葡萄糖醛酸苷用途

孕二醇3-葡萄糖醛酸是孕酮的主要终末代谢产物,在生理过程中发挥重要作用,如女性月经周期、妊娠(支持妊娠)、胚胎发生和人类及其他物种的母体免疫反应[1]。

妊娠二醇3Α单葡萄糖醛酸苷名称

[ CAS 号 ]:
1852-49-9

[ 中文名 ]:
3-Alpha,20alpha-二羟基-5beta-孕甾3-葡糖苷酸

[ 英文名 ]:
Pregnanediol 3-glucuronide

[英文别名 ]:

妊娠二醇3Α单葡萄糖醛酸苷生物活性

[ 描述 ]:

[ 相关类别 ]:

研究领域 >> 内分泌

[ 靶点 ]

Human Endogenous Metabolite

[参考文献]

[1]. Chen J, et al. Quantitation of serum pregnanediol-3-glucuronide level in different endocrine statuses by LC-MS/MS. J Pharm Biomed Anal. 2020;184:113171.

妊娠二醇3Α单葡萄糖醛酸苷物理化学性质

[ 密度 ]:
1.3g/cm3

[ 沸点 ]:
666.4ºC at 760mmHg

[ 熔点 ]:
>94°C (dec.) (lit.)

[ 分子式 ]:
C₂₇H₄₄O₈

[ 分子量 ]:
496.63300

[ 闪点 ]:
217.2ºC

[ 精确质量 ]:
496.30400

[ PSA ]:
136.68000

[ LogP ]:
2.30350

[ 外观性状 ]:
白色至浅米色固体

[ 蒸汽压 ]:
1.34E-20mmHg at 25°C

[ 折射率 ]:
1.587

[ 储存条件 ]:
20°C，惰性气体

妊娠二醇3Α单葡萄糖醛酸苷安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

妊娠二醇3Α单葡萄糖醛酸苷合成路线

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妊娠二醇3Α单葡萄糖醛酸苷文献

Progesterone, pregnanediol-3-glucuronide, relaxin and oestrone sulphate concentrations in saliva, milk and urine of female alpacas (Vicugna pacos) and their application in pregnancy diagnosis.

Vet. Rec. 171(8) , 195, (2012)

The pregnancy-associated hormones, progesterone (P4), pregnanediol-3-glucuronide (PdG), relaxin (RLN) and oestrone sulphate (E1S) in plasma, saliva, milk and urine of alpacas were measured in order to...

Factors related to declining luteal function in women during the menopausal transition.

J. Clin. Endocrinol. Metab. 93(5) , 1711-21, (2008)

Reproductive hormones are incompletely characterized during the menopause transition (MT).Increased anovulation and decreased progesterone accompany progress through the MT.The Daily Hormone Study (DH...

Describing ovarian cycles, pregnancy characteristics, and the use of contraception in female white-faced marmosets, Callithrix geoffroyi.

Am. J. Primatol. 74(11) , 1044-53, (2012)

Endocrine data and characteristics of nonconceptive ovarian cycling and pregnancy are limited within the genus Callithrix to the common marmoset (C. jacchus) and Wied's black tufted-ear marmoset (C. k...

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