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花生四烯酰辅酶 A 锂盐

花生四烯酰辅酶 A 锂盐用途

花生四烯酸辅酶A锂是一种不饱和脂肪酰辅酶A,由辅酶A的巯基与花生四烯酸羧基缩合而成[1]。

花生四烯酰辅酶 A 锂盐名称

[ CAS 号 ]:
188174-63-2

[ 中文名 ]:
顺,顺,顺,顺-5,8,11,14-二十碳四烯酰辅酶 A 锂盐

[ 英文名 ]:
arachidonoyl coenzyme a (c20:4) lithium salt

[中文别名 ]:

花生酰辅酶A

[英文别名 ]:

Arachidonoyl coenzyme A lithium salt
Arachidonoyl coenzyme A lithium salt

花生四烯酰辅酶 A 锂盐生物活性

[ 描述 ]:

花生四烯酸辅酶A锂是一种不饱和脂肪酰辅酶A,由辅酶A的巯基与花生四烯酸羧基缩合而成[1]。

[ 相关类别 ]:

研究领域 >> 代谢疾病

[体内研究]

花生酰辅酶A锂在不同区域的合成活性不同,其在匀浆和微粒体中的合成高于小脑和脑干,而在突触质膜中的合成较低,在荷包牡丹碱诱导的雄性Wistar大鼠癫痫持续状态中未发生变化[1]。

[参考文献]

[1]. T S Reddy, et al. Synthesis of arachidonoyl coenzyme A and docosahexaenoyl coenzyme A in synaptic plasma membranes of cerebrum and microsomes of cerebrum, cerebellum, and brain stem of rat brain. J Neurosci Res. 1985;13(3):381-90.

花生四烯酰辅酶 A 锂盐物理化学性质

[ 分子式 ]:
C₄₁H₆₅LiN₇O₁₇P₃S

[ 分子量 ]:
1059.92000

[ 精确质量 ]:
1059.35000

[ PSA ]:
428.17000

[ LogP ]:
6.94470

[ 储存条件 ]:
−20°C

花生四烯酰辅酶 A 锂盐MSDS

详细MSDS(安全技术说明书)

花生四烯酰辅酶 A 锂盐安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

花生四烯酰辅酶 A 锂盐文献

Identification of glycine N-acyltransferase-like 2 (GLYATL2) as a transferase that produces N-acyl glycines in humans.

FASEB J. 24 , 2795-2803, (2010)

The discovery of glycine conjugates of long-chain fatty acids (N-acyl glycines) in the brain and other non-neuronal tissues has led to the identification of an emerging class of bioactive lipids. The ...

CGI-58/ABHD5 is a coenzyme A-dependent lysophosphatidic acid acyltransferase.

J. Lipid Res. 51 , 709-719, (2010)

Mutations in human CGI-58/ABHD5 cause Chanarin-Dorfman syndrome (CDS), characterized by excessive storage of triacylglycerol in tissues. CGI-58 is an alpha/beta-hydrolase fold enzyme expressed in all ...

Arachidonic acid stimulates extracellular Ca(2+) entry in rat pancreatic beta cells via activation of the noncapacitative arachidonate-regulated Ca(2+) (ARC) channels.

Cell Calcium 47 , 77-83, (2010)

Arachidonic acid (AA) is generated in the pancreatic islets during glucose stimulation. We investigated whether AA activated extracellular Ca(2+) entry in rat pancreatic beta cells via a pathway that ...

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