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2,6-二氨基嘌呤

2,6-二氨基嘌呤用途

7H-嘌呤-2,6-二胺是一种生物化学试剂,可作为生物材料或有机化合物用于生命科学相关研究。

2,6-二氨基嘌呤名称

[ CAS 号 ]:
1904-98-9

[ 中文名 ]:
2,6-二氨基嘌呤

[ 英文名 ]:
2,6-Diaminopurine

[中文别名 ]:

[英文别名 ]:

26DAPY
2,6-diamino-purin
2,6-diamino purine
1H-Purine-2,6-diamine
7H-Purine-2,6-diamine
MFCD00071537
diaminopurine
2,6-Daminopurine
EINECS 205-507-2
2-Aminoadenine

2,6-二氨基嘌呤生物活性

[ 描述 ]:

7H-嘌呤-2,6-二胺是一种生物化学试剂,可作为生物材料或有机化合物用于生命科学相关研究。

[ 相关类别 ]:

研究领域 >> 其他

[体外研究]

2,6-二氨基嘌呤是一种用于研究白血病的化合物。

2,6-二氨基嘌呤物理化学性质

[ 密度 ]:
1.7±0.1 g/cm3

[ 沸点 ]:
749.0±63.0 °C at 760 mmHg

[ 熔点 ]:
117-122 °C(lit.)

[ 分子式 ]:
C₅H₆N₆

[ 分子量 ]:
150.14

[ 闪点 ]:
447.8±20.9 °C

[ 精确质量 ]:
150.065399

[ PSA ]:
106.50000

[ LogP ]:
-0.21

[ 外观性状 ]:
淡黄色粉末

[ 蒸汽压 ]:
0.0±2.5 mmHg at 25°C

[ 折射率 ]:
1.940

[ 储存条件 ]:
室温

[ 水溶解性 ]:
2.38 g/L (20 ºC)

2,6-二氨基嘌呤MSDS

2,6-二氨基嘌呤毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UO7524000

CHEMICAL NAME :: Purine, 2,6-diamino-

CAS REGISTRY NUMBER :: 1904-98-9

LAST UPDATED :: 199701

DATA ITEMS CITED :: 8

MOLECULAR FORMULA :: C5-H6-N6

MOLECULAR WEIGHT :: 150.17

WISWESSER LINE NOTATION :: T56 BN DN FN HMJ GZ IZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 202 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD10 - Lethal Dose

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 70 mg/kg

TOXIC EFFECTS :: Blood - changes in bone marrow (not otherwise specified)

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Microorganism - not otherwise specified

DOSE/DURATION :: 500 mg/L

REFERENCE :: SOGEBZ Soviet Genetics. English translation of GNKAA5. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) V.2- 1966- Volume(issue)/page/year: 6,1509,1970

2,6-二氨基嘌呤安全信息

[ 符号 ]:

GHS07, GHS08

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302 + H312 + H332-H315-H319-H335-H351

[ 警示性声明 ]:
P261-P280-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xn:Harmful

[ 风险声明 (欧洲) ]:
R40

[ 安全声明 (欧洲) ]:
S26-S45-S36/37-S36/37/39-S27

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
US7570000

[ 海关编码 ]:
2933990090

2,6-二氨基嘌呤合成路线

2,6-二氨基嘌呤上下游产品

2,6-二氨基嘌呤上游产品

2,6-二氨基嘌呤下游产品

2,6-二氨基嘌呤海关

[ 海关编码 ]: 2933990090

[ 中文概述 ]:
2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

2,6-二氨基嘌呤文献

Effect of substituents on the excited-state dynamics of the modified DNA bases 2,4-diaminopyrimidine and 2,6-diaminopurine.

Phys. Chem. Chem. Phys. 12(20) , 5375-88, (2010)

To explore the excited state dynamics of pyrimidine derivatives, we performed a combined experimental and theoretical study. We present resonant two-photon ionization (R2PI) and IR-UV double resonance...

Formation and helicity control of ssDNA templated porphyrin nanoassemblies.

Chem. Commun. (Camb.) 49(10) , 1020-2, (2013)

We report the formation of left- (M-helix) and right-handed (P-helix) nanoassemblies of a porphyrin-diaminopurine conjugate (Por-DAP) templated by a single stranded oligodeoxythymidine (dT40) via dire...

Simulations of A-RNA duplexes. The effect of sequence, solute force field, water model, and salt concentration.

J. Phys. Chem. B 116(33) , 9899-916, (2012)

We have carried out an extended reference set of explicit solvent molecular dynamics simulations (63 simulations with 8.4 μs of simulation data) of canonical A-RNA duplexes. Most of the simulations we...

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