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乙酰胆碱碘化物

乙酰胆碱碘化物用途

Acetylcholine iodide是在中枢和外周神经系统中常见的神经递质。

乙酰胆碱碘化物名称

[ CAS 号 ]:
2260-50-6

[ 中文名 ]:
碘化乙酰胆碱

[ 英文名 ]:
2-Acetoxy-N,N,N-trimethylethanaminium iodide

[中文别名 ]:

[英文别名 ]:

[14C]-Acetylcholine iodide
acetylthiocholine iodide
(2-Acetoxyethyl)trimethylammonium iodide
Acetylcolina [Italian]
acetylcholin iodide
Choline,iodide,acetate (ester)
Acetylcholine iodide
EINECS 218-862-3
MFCD00011815
2-Acetoxy-N,N,N-trimethylethanaminium iodide

乙酰胆碱碘化物生物活性

[ 描述 ]:

Acetylcholine iodide是在中枢和外周神经系统中常见的神经递质。

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

研究领域 >> 神经疾病

[参考文献]

[1]. MEITES J, et al. Induction and maintenance of mammary growth and lactation in rats with acetylcholine or epinephrine. Proc Soc Exp Biol Med. 1959 Apr;100(4):750-4.

乙酰胆碱碘化物物理化学性质

[ 熔点 ]:
161-164 °C

[ 分子式 ]:
C₇H₁₆INO₂

[ 分子量 ]:
273.112

[ 精确质量 ]:
273.022552

[ PSA ]:
26.30000

[ 外观性状 ]:
白色结晶粉末

[ 储存条件 ]:
2-8°C

乙酰胆碱碘化物MSDS

乙酰胆碱碘化物毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KH3300000

CHEMICAL NAME :: Ethanamium, 2-(acetyloxy)-N,N,N-trimethyl-, iodide

CAS REGISTRY NUMBER :: 2260-50-6

LAST UPDATED :: 199701

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C7-H16-N-O2.I

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >1500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 23,887,1989

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 155 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 21,51,1966

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 18 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: IJNEAQ International Journal of Neuropharmacology. (New York, NY) V.1-8, 1962-69. For publisher information, see NEPHBW. Volume(issue)/page/year: 8,131,1969

乙酰胆碱碘化物安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302-H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi: Irritant;

[ 风险声明 (欧洲) ]:
36/37/38

[ 安全声明 (欧洲) ]:
S26

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
KH3300000

[ 海关编码 ]:
2923900090

乙酰胆碱碘化物合成路线

乙酰胆碱碘化物上下游产品

乙酰胆碱碘化物上游产品

乙酰胆碱碘化物下游产品

乙酰胆碱碘化物制备

酒石酸胆碱经氢氧化钡作用生成胆碱，后者再经碘化、乙酰化制得。

乙酰胆碱碘化物海关

[ 海关编码 ]: 2923900090

[ 中文概述 ]:
2923900090 其他季铵盐及季铵碱。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:6.5%。普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2923900090 other quaternary ammonium salts and hydroxides。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

乙酰胆碱碘化物文献

Tibolone prevents oxidation and ameliorates cholinergic deficit induced by ozone exposure in the male rat hippocampus.

Neurochem. Res. 39(9) , 1776-86, (2014)

Oxidative stress is related to the development of central nervous system diseases involving memory processes. Cholinergic system and memory processes are disrupted by ozone exposure. In rats, ozone in...

Chloroform extract of underground parts of Ferula heuffelii: secondary metabolites and spasmolytic activity.

Chem. Biodivers. 11(9) , 1417-27, (2014)

Plants from the genus Ferula L. (Apiaceae) were used for various purposes in traditional medicine of different nations throughout the history. Ferula heuffelii Griseb. ex Heuffel is a perennial specie...

Protective Effect of Lavandula stoechas and Rosmarinus officinalis essential oils against reproductive damage and oxidative stress in alloxan-induced diabetic rats.

J. Med. Food 18(2) , 241-9, (2015)

The authors aimed in the present study to assess the protective effect of Rosmarinus officinalis essential oils (ROEO) and Lavandula stoechas essential oils (LSEO) against reproductive damage and oxid...

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