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二十二碳五烯酸

二十二碳五烯酸用途

Docosapentaenoic acid (22n-3) 是所有动物细胞膜中发现的磷脂组成成分。

二十二碳五烯酸名称

[ CAS 号 ]:
24880-45-3

[ 中文名 ]:
顺-7,10,13,16,19-二十二碳五稀酸

[ 英文名 ]:
Docosapentaenoic acid (22:5(n-3))

[中文别名 ]:

[英文别名 ]:

all-cis-7,10,13,16,19-Docosapentaenoic acid
CIS-7,10,13,16,19-DOCOSA-PENTAENOIC ACID
Docosapentaenoic acid (22:5(n-3))
(7Z,10Z,13Z,16Z,19Z)-Docosapentaenoic acid
MFCD00156103

二十二碳五烯酸生物活性

[ 描述 ]:

Docosapentaenoic acid (22n-3) 是所有动物细胞膜中发现的磷脂组成成分。

[ 相关类别 ]:

研究领域 >> 代谢疾病

天然产物 >> 其他

[ 靶点 ]

Human Endogenous Metabolite

[参考文献]

[1]. Sinclair HM, et al. Essential fatty acids in perspective. Hum Nutr Clin Nutr. 1984 Jul;38(4):245-60.

[相关活性小分子]

二十二碳五烯酸物理化学性质

[ 密度 ]:
0.9±0.1 g/cm3

[ 沸点 ]:
442.2±24.0 °C at 760 mmHg

[ 分子式 ]:
C₂₂H₃₄O₂

[ 分子量 ]:
330.504

[ 闪点 ]:
338.9±18.0 °C

[ 精确质量 ]:
330.255890

[ PSA ]:
37.30000

[ LogP ]:
7.26

[ 蒸汽压 ]:
0.0±2.3 mmHg at 25°C

[ 折射率 ]:
1.509

二十二碳五烯酸MSDS

详细MSDS(安全技术说明书)

二十二碳五烯酸毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: JR1320000

CHEMICAL NAME :: 7,10,13,16,19-Docosapentaenoic acid, (all Z)-

CAS REGISTRY NUMBER :: 24880-45-3

LAST UPDATED :: 199106

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C22-H34-O2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >20 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970- Volume(issue)/page/year: 20,801,1989

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >20 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970- Volume(issue)/page/year: 20,801,1989

二十二碳五烯酸安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

[ RTECS号 ]:
JR1320000

二十二碳五烯酸文献

Interference by naturally occurring fatty acids in a noncellular enzyme-based aromatase bioassay.

J. Nat. Prod. 69 , 700-3, (2006)

Natural product drug discovery efforts frequently utilize noncellular screening assays. Fatty acids are commonly found in natural product extracts, and some have been shown to interfere with noncellul...

Regulation of the biosynthesis of 4,7,10,13,16-docosapentaenoic acid.

Biochem. J. 326 ( Pt 2) , 425-30, (1997)

It is now established that fatty acid 7,10,13,16-22:4 is metabolized into 4,7,10,13,16-22:5 as follows: 7,10,13,16-22:4-->9,12,15, 18-24:4-->6,9,12,15,18-24:5-->4,7,10,13,16-22:5. Neither C24 fatty ac...

The metabolism of 7,10,13,16,19-docosapentaenoic acid to 4,7,10,13,16,19-docosahexaenoic acid in rat liver is independent of a 4-desaturase.

J. Biol. Chem. 266(30) , 19995-20000, (1991)

The hypothesis that the last step in the biosynthesis of 4,7,10,13,16,19-22:6 from linolenate is catalyzed by an acyl-CoA-dependent 4-desaturase has never been evaluated by direct experimentation. Whe...

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