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4,4-二羟基二苯硫醚

4,4-二羟基二苯硫醚用途

【用途一】
用于有机合成

4,4-二羟基二苯硫醚名称

[ CAS 号 ]:
2664-63-3

[ 中文名 ]:
4,4'-二羟基二苯硫醚

[ 英文名 ]:
4,4′-Thiodiphenol

[中文别名 ]:

[英文别名 ]:

Bis(4-hydroxyphenyl) sulfide
Thiobisphenol
4,4'-Thiobisphenol
MFCD00002349
Phenol, 4,4'-thiobis-
4-(4-hydroxyphenyl)sulfanylphenol
4-hydroxyphenyl sulphide
p,p'-Dihydroxydiphenyl sulfide
4,4′-Thiodiphenol
4,4'-thiodiphenol

4,4-二羟基二苯硫醚物理化学性质

[ 密度 ]:
1.4±0.1 g/cm3

[ 沸点 ]:
452.7±30.0 °C at 760 mmHg

[ 熔点 ]:
154-156 °C(lit.)

[ 分子式 ]:
C₁₂H₁₀O₂S

[ 分子量 ]:
218.272

[ 闪点 ]:
219.7±23.3 °C

[ 精确质量 ]:
218.040146

[ PSA ]:
65.76000

[ LogP ]:
3.34

[ 外观性状 ]:
白色片状晶体

[ 蒸汽压 ]:
0.0±1.1 mmHg at 25°C

[ 折射率 ]:
1.717

[ 储存条件 ]:
存放于惰性气体之中;避免空气

[ 水溶解性 ]:
水溶性：不溶；可溶于：乙醚,醇

4,4-二羟基二苯硫醚MSDS

4,4-二羟基二苯硫醚毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SN0800000

CHEMICAL NAME :: Phenol, 4,4'-thiodi-

CAS REGISTRY NUMBER :: 2664-63-3

LAST UPDATED :: 199710

DATA ITEMS CITED :: 9

MOLECULAR FORMULA :: C12-H10-O2-S

MOLECULAR WEIGHT :: 218.28

WISWESSER LINE NOTATION :: QR DSR DQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: BIOFX* BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. (1810 Frontage Rd., Northbrook, IL 60062) Volume(issue)/page/year: A408,1971

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: BIOFX* BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. (1810 Frontage Rd., Northbrook, IL 60062) Volume(issue)/page/year: A408,1971 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3362 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BIOFX* BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. (1810 Frontage Rd., Northbrook, IL 60062) Volume(issue)/page/year: A408,1971

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 5500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TPKVAL Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. (Izdatel'stvo Meditsina, Moscow, USSR) No.1- 1961- Volume(issue)/page/year: 13,154,1973

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >10250 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BIOFX* BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. (1810 Frontage Rd., Northbrook, IL 60062) Volume(issue)/page/year: A408,1971 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 3 mg/m3 JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - T0044 No. of Facilities: 69 (estimated) No. of Industries: 3 No. of Occupations: 3 No. of Employees: 1146 (estimated)

4,4-二羟基二苯硫醚安全信息

[ 符号 ]:

GHS05

[ 信号词 ]:
Danger

[ 危害声明 ]:
H314

[ 警示性声明 ]:
P280-P305 + P351 + P338-P310

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ 危害码 (欧洲) ]:
C:Corrosive;

[ 风险声明 (欧洲) ]:
R34

[ 安全声明 (欧洲) ]:
S26-S27-S36/37/39-S45

[ 危险品运输编码 ]:
UN 3261 8/PG 2

[ WGK德国 ]:
2

[ RTECS号 ]:
SN0800000

[ 包装等级 ]:
II

[ 危险类别 ]:
8

[ 海关编码 ]:
29309070

4,4-二羟基二苯硫醚合成路线

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4,4-二羟基二苯硫醚海关

[ 海关编码 ]: 29309070

4,4-二羟基二苯硫醚文献

Screening of bisphenol A, triclosan and paraben analogues as modulators of the glucocorticoid and androgen receptor activities.

Toxicol. In Vitro 29(1) , 8-15, (2014)

A homeostasis of the glucocorticoid and androgen endocrine system is essential to human health. Their disturbance can lead to various diseases, for example cardiovascular, inflammatory and autoimmune ...

[Materials for the establishment of maximum allowable concentrations of bis (4-oxyphenyl) sulfide in the working zone air].

Gig. Tr. Prof. Zabol. (1) , 31-2, (1991)

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