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DL-丝氨酸

DL-丝氨酸用途

DL-Serine是D-丝氨酸和L-丝氨酸的混合物。

DL-丝氨酸名称

[ CAS 号 ]:
302-84-1

[ 中文名 ]:
DL-丝氨酸

[ 英文名 ]:
DL-Serine

[中文别名 ]:

[英文别名 ]:

2-Amino-3-Hydroxypropionicacid
Serine,dl
SERINE, (L)
DL-Serine
MFCD00064223
H-DL-SER-OH
DL-2-Amino-3-hydroxypropionic Acid
SERINE
DL-Serin
DL-SER

DL-丝氨酸生物活性

[ 描述 ]:

DL-Serine是D-丝氨酸和L-丝氨酸的混合物。

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

天然产物 >> 酸和醛

研究领域 >> 癌症

[体内研究]

皮下注射DL-丝氨酸增加了用500或1,000ppm N-乙基-N-羟乙基亚硝胺处理的雄性W大鼠的肾小管细胞肿瘤的数量和大小[1]。

[参考文献]

[1]. Hiasa Y, et al. DL-Serine: promoting activity on renal tumorigenesis by N-ethyl-N-hydroxyethylnitrosamine in rats. J Natl Cancer Inst. 1984 Jul;73(1):297-9.

[相关活性小分子]

DL-丝氨酸物理化学性质

[ 密度 ]:
1.4±0.1 g/cm3

[ 沸点 ]:
394.8±32.0 °C at 760 mmHg

[ 熔点 ]:
240ºC (dec.)

[ 分子式 ]:
C₃H₇NO₃

[ 分子量 ]:
105.093

[ 闪点 ]:
192.6±25.1 °C

[ 精确质量 ]:
105.042595

[ PSA ]:
83.55000

[ LogP ]:
-1.58

[ 外观性状 ]:
白色晶体

[ 蒸汽压 ]:
0.0±2.1 mmHg at 25°C

[ 折射率 ]:
1.519

[ 储存条件 ]:
Store at RT.

[ 水溶解性 ]:
50.23 g/L (25 ºC)

DL-丝氨酸MSDS

详细MSDS(安全技术说明书)

DL-丝氨酸安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xi

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
VT8100000

[ 海关编码 ]:
2922509090

DL-丝氨酸合成路线

详细合成路线

DL-丝氨酸上下游产品

DL-丝氨酸上游产品

DL-丝氨酸下游产品

DL-丝氨酸制备

1.L-丝氨酸的制取方法有三种。一是由L-丝氨酸含量多的蛋白质水解后，由离子交换树脂分离和精制而得；二是由甲酸乙酯与马尿酸乙酯反应而得；三是以糖类为原料，由发酵法制得。

DL-丝氨酸海关

[ 海关编码 ]: 2922509090

[ 中文概述 ]:
2922509090. 其他氨基醇酚、氨基酸酚及其他含氧基氨基化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件：AB. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装

[ 监管条件 ]: A.入境货物通关单 B.出境货物通关单

[ 检验检疫 ]: R.进口食品卫生监督检验 S.出口食品卫生监督检验

[ Summary ]:
2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

DL-丝氨酸文献

Activation of Tomato Bushy Stunt Virus RNA-Dependent RNA Polymerase by Cellular Heat Shock Protein 70 Is Enhanced by Phospholipids In Vitro.

J. Virol. 89(10) , 5714-23, (2015)

Similar to other positive-strand RNA viruses, tombusviruses are replicated by the membrane-bound viral replicase complex (VRC). The VRC consists of the p92 virus-coded RNA-dependent RNA polymerase (Rd...

Intrinsic mechanisms underlying the neurotrophic activity of adipose derived stem cells.

Exp. Cell Res. 331(1) , 142-51, (2015)

Adipose derived stem cells (ADSC) can be differentiated into Schwann cell-like cells which enhance nerve function and regeneration. However, the signalling mechanisms underlying the neurotrophic poten...

Rad23 interaction with the proteasome is regulated by phosphorylation of its ubiquitin-like (UbL) domain.

J. Mol. Biol. 426(24) , 4049-60, (2014)

Rad23 was identified as a DNA repair protein, although a role in protein degradation has been described. The protein degradation function of Rad23 contributes to cell cycle progression, stress respons...

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