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2,3-二羟基苯甲酸

2,3-二羟基苯甲酸用途

Pyrocatechuic acid 是存在于血浆中的苯甲酸代谢物,当摄入阿司匹林后,它的含量会增加。

2,3-二羟基苯甲酸名称

[ CAS 号 ]:
303-38-8

[ 中文名 ]:
2,3-二羟基苯甲酸

[ 英文名 ]:
2,3-Dihydroxybenzoic acid

[中文别名 ]:

[英文别名 ]:

catecholcarboxylicacid
2,3-DIAMIDOXIMO-1,4-DIHYDROXYNAPHTHALENE
Catechol-3-carboxylic Acid
2,3-dihydroxybenzoate
EINECS 206-139-5
O-PYROCATECHUIC ACID
di-hydroxybenzoic acid
2-pyrocatechuicacid
pyrocatechuic acid
Benzoic acid, 2,3-dihydroxy-

2,3-二羟基苯甲酸生物活性

[ 描述 ]:

Pyrocatechuic acid 是存在于血浆中的苯甲酸代谢物,当摄入阿司匹林后,它的含量会增加。

[ 相关类别 ]:

研究领域 >> 其他

[ 靶点 ]

Human Endogenous Metabolite

[体外研究]

Pyrocatechuic acid(2,3-Dihydroxybenzoic acid)是血浆中发现的正常人苯甲酸代谢物,摄入阿司匹林后水平升高[1]。

[参考文献]

[1]. Grootveld M, et al. 2,3-Dihydroxybenzoic acid is a product of human aspirin metabolism. Biochem Pharmacol. 1988 Jan 15;37(2):271-80.

[相关活性小分子]

2,3-二羟基苯甲酸物理化学性质

[ 密度 ]:
1.6±0.1 g/cm3

[ 沸点 ]:
362.5±32.0 °C at 760 mmHg

[ 熔点 ]:
204-206 °C(lit.)

[ 分子式 ]:
C₇H₆O₄

[ 分子量 ]:
154.120

[ 闪点 ]:
187.2±21.6 °C

[ 精确质量 ]:
154.026611

[ PSA ]:
77.76000

[ LogP ]:
1.80

[ 外观性状 ]:
白色结晶粉末

[ 蒸汽压 ]:
0.0±0.9 mmHg at 25°C

[ 折射率 ]:
1.671

[ 储存条件 ]:
2-8°C

2,3-二羟基苯甲酸MSDS

2,3-二羟基苯甲酸毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DG8576490

CHEMICAL NAME :: Benzoic acid, 2,3-dihydroxy-

CAS REGISTRY NUMBER :: 303-38-8

BEILSTEIN REFERENCE NO. :: 2209117

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C7-H6-O4

MOLECULAR WEIGHT :: 154.13

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >3 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 196,478,1976

2,3-二羟基苯甲酸安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi:Irritant

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36-S37/39

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
2

[ RTECS号 ]:
DG8576490

[ 海关编码 ]:
2918290000

2,3-二羟基苯甲酸合成路线

2,3-二羟基苯甲酸上下游产品

2,3-二羟基苯甲酸上游产品

2,3-二羟基苯甲酸下游产品

2,3-二羟基苯甲酸海关

[ 海关编码 ]: 2918290000

[ 中文概述 ]:
2918290000 其他含酚基但不含其他含氧基羧酸及其酸酐、酰卤化物、过氧化物和过氧酸及它们的衍生物。监管条件:AB(入境货物通关单,出境货物通关单)。增值税率:17.0%。退税率:9.0%。最惠国关税:6.5%。普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ 监管条件 ]: A.入境货物通关单 B.出境货物通关单

[ 检验检疫 ]: R.进口食品卫生监督检验 S.出口食品卫生监督检验

[ Summary ]:
HS: 2918290000 other carboxylic acids with phenol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) VAT:17.0% MFN tariff:6.5% General tariff:30.0%

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