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L-硒代蛋氨酸

L-硒代蛋氨酸用途

L-SelenoMethionine是一种重要的天然食品形态硒, 是重要的有机硒源之一。

L-硒代蛋氨酸名称

[ CAS 号 ]:
3211-76-5

[ 中文名 ]:
L-硒代蛋氨酸

[ 英文名 ]:
L-Selenomethionine

[中文别名 ]:

[英文别名 ]:

L-Selenomethioninum
(2S)-2-Amino-4-(methylseleno)butanoic acid
(S)-2-Amino-4-(Methylseleno)Butyric Acid
MFCD00037210
(2S)-2-Amino-4-(methylselanyl)butanoic acid
Selenium-L-methionine
Se-methionine
SeMet
L-selenomethionine zwitterion
(S)-2-Amino-4-(methylselanyl)butanoic acid

L-硒代蛋氨酸生物活性

[ 描述 ]:

L-SelenoMethionine是一种重要的天然食品形态硒, 是重要的有机硒源之一。

[ 相关类别 ]:

天然产物 >> 其他

研究领域 >> 其他

[ 靶点 ]

Human Endogenous Metabolite

[参考文献]

[1]. Schrauzer GN, et al. Selenomethionine: a review of its nutritional significance, metabolism and toxicity. J Nutr. 2000 Jul;130(7):1653-1656.

[相关活性小分子]

L-硒代蛋氨酸物理化学性质

[ 沸点 ]:
320.8±37.0 °C at 760 mmHg

[ 熔点 ]:
265 °C

[ 分子式 ]:
C₅H₁₁NO₂Se

[ 分子量 ]:
196.106

[ 闪点 ]:
147.8±26.5 °C

[ 精确质量 ]:
196.995499

[ PSA ]:
63.32000

[ LogP ]:
-0.65

[ 外观性状 ]:
白色至灰白色粉末

[ 蒸汽压 ]:
0.0±1.5 mmHg at 25°C

[ 折射率 ]:
18 ° (C=0.5, 2mol/L HCl)

[ 储存条件 ]:
<0°C;存放于惰性气体之中;避免空气,湿气 (吸湿),加热

[ 水溶解性 ]:
soluble

L-硒代蛋氨酸MSDS

L-硒代蛋氨酸毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: EK7713840

CHEMICAL NAME :: Butanoic acid, 2-amino-4-(methylseleno)-, (S)-

CAS REGISTRY NUMBER :: 3211-76-5

LAST UPDATED :: 199707

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C5-H11-N-O2-Se

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 269 mg/kg/8W-C

TOXIC EFFECTS :: Liver - other changes Nutritional and Gross Metabolic - weight loss or decreased weight gain

REFERENCE :: JTEMEM Journal of Trace Elements in Experimental Medicine. (Wiley-Liss, Inc., 605 Third Ave., New York, NY 10158-0012) V.1- 1988- Volume(issue)/page/year: 4,69,1991

L-硒代蛋氨酸安全信息

[ 符号 ]:

GHS06, GHS08, GHS09

[ 信号词 ]:
Danger

[ 危害声明 ]:
H301 + H331-H373-H410

[ 警示性声明 ]:
Missing Phrase - N15.00950417-P260-P304 + P340 + P312-P403 + P233

[ 危害码 (欧洲) ]:
T:Toxic;N:Dangerousfortheenvironment;

[ 风险声明 (欧洲) ]:
R23/25;R33;R50/53

[ 安全声明 (欧洲) ]:
S20/21-S28-S45-S60-S61-S28A

[ 危险品运输编码 ]:
UN 3283 6.1/PG 2

[ WGK德国 ]:
3

[ RTECS号 ]:
EK7713840

[ 包装等级 ]:
I; II; III

[ 危险类别 ]:
6.1

[ 海关编码 ]:
2922499990

L-硒代蛋氨酸合成路线

L-硒代蛋氨酸上下游产品

L-硒代蛋氨酸上游产品

L-硒代蛋氨酸下游产品

L-硒代蛋氨酸海关

[ 海关编码 ]: 2922499990

[ 中文概述 ]:
2922499990 其他氨基酸及其酯及它们的盐（含有一种以上含氧基的除外）. 增值税率:17.0% 退税率:9.0% 监管条件:AB(入境货物通关单,出境货物通关单) 最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装

[ 监管条件 ]: A.入境货物通关单 B.出境货物通关单

[ 检验检疫 ]: P.进境动植物、动植物产品检疫 Q.出境动植物、动植物产品检疫 R.进口食品卫生监督检验 S.出口食品卫生监督检验 M.进口商品检验 N.出口商品检验

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

L-硒代蛋氨酸文献

Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.

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Drug-induced liver injury is one of the main causes of drug attrition. The ability to predict the liver effects of drug candidates from their chemical structures is critical to help guide experimental...

Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression.

Nature 457(7231) , 910-4, (2009)

Multiple, complex molecular events characterize cancer development and progression. Deciphering the molecular networks that distinguish organ-confined disease from metastatic disease may lead to the i...

Structure of the Ergothioneine-Biosynthesis Amidohydrolase EgtC.

ChemBioChem. 16 , 1490-6, (2015)

The ubiquitous sulfur metabolite ergothioneine is biosynthesized by oxidative attachment of a sulfur atom to the imidazole ring of Nα-trimethylhistidine. Most actinobacteria, including Mycobacterium t...

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