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7-(对甲氧基苄氨基)-4-硝基苯-2-恶唑-1,3-二唑

用途

MBD(7-(对甲氧基苄基氨基)-4-硝基苯-2,1,3-恶二唑)是一种新的蛋白质和核蛋白构象荧光探针,用于细菌核糖体、牛胰蛋白酶原和胰蛋白酶。MBD结合到大分子的疏水区域时具有强荧光[1][2]。

名称

[ CAS 号 ]:
33984-50-8

[ 中文名 ]:
4-(对甲氧基苄氨基)-7-硝基-2,1,3-苯并噁二唑

[ 英文名 ]:
7-(4-Methoxybenzylamino)-4-nitrobenzoxadiazole

[中文别名 ]:

4-(4-甲氧基苯氨基)-7-硝基苯呋咱

[英文别名 ]:

Benzofurazan,4-((p-methoxybenzyl)amino)-7-nitro
4-(4-Methoxybenzylamino)-7-nitrobenzofurazan
t56 bnonj fnw im1r do1[wln]
4-(4-methoxybenzylamino)-7-nitrobenzofurazane
MFCD00042778
EINECS 251-775-9
MBD

生物活性

[ 描述 ]:

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[参考文献]

[1]. Kenner RA, et al. A new fluorescent probe for protein and nucleoprotein conformation. Binding of 7-(p-methoxybenzylamino)-4-nitrobenzoxadiazole to bovine trypsinogen and bacterial ribosomes. Biochemistry. 1971;10(24):4433-4440.

[2]. Kasahara Y, et al. Formation of a conformationally changed C1r, a subcomponent of the first component of human complement, as an intermediate of its autoactivation reaction. FEBS Lett. 1982;141(1):128-131.

物理化学性质

[ 密度 ]:
1.438 g/cm3

[ 沸点 ]:
500.8ºC at 760 mmHg

[ 熔点 ]:
178-182ºC

[ 分子式 ]:
C₁₄H₁₂N₄O₄

[ 分子量 ]:
300.26900

[ 闪点 ]:
256.7ºC

[ 精确质量 ]:
300.08600

[ PSA ]:
106.00000

[ LogP ]:
3.34790

[ 外观性状 ]:
橙色至棕色粉末

[ 折射率 ]:
1.691

MSDS

详细MSDS(安全技术说明书)

安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 安全声明 (欧洲) ]:
22-24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ 海关编码 ]:
2934999090

海关

[ 海关编码 ]: 2934999090

[ 中文概述 ]:
2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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