<生产厂家价格>

新茄病镰刀菌烯醇

新茄病镰刀菌烯醇用途

Neosolaniol 是一种来自于镰刀菌霉菌的 A 型单端孢霉菌真菌毒素。Neosolaniol 会引起强烈的厌食反应。

新茄病镰刀菌烯醇名称

[ CAS 号 ]:
36519-25-2

[ 中文名 ]:
新茄病镰刀菌烯醇

[ 英文名 ]:
Neosolaniol

[中文别名 ]:

新茄镰孢菌醇

[英文别名 ]:

Solaniol (van)
8-HYDROXYDIACETOXYSCIRPENOL
neosolaniol solution
Neosalaniol
NEOSOLANIOL

新茄病镰刀菌烯醇生物活性

[ 描述 ]:

Neosolaniol 是一种来自于镰刀菌霉菌的 A 型单端孢霉菌真菌毒素。Neosolaniol 会引起强烈的厌食反应。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[参考文献]

[1]. McCormick SP, et al. Trichothecenes: from simple to complex mycotoxins. Toxins (Basel). 2011 Jul;3(7):802-14.

[2]. Zhang J, et al. Comparison of Anorectic Potencies of Type A Trichothecenes T-2 Toxin, HT-2 Toxin, Diacetoxyscirpenol, and Neosolaniol. Toxins (Basel). 2018 Apr 29;10(5).

新茄病镰刀菌烯醇物理化学性质

[ 密度 ]:
1.4±0.1 g/cm3

[ 沸点 ]:
515.9±50.0 °C at 760 mmHg

[ 熔点 ]:
171.5°C

[ 分子式 ]:
C₁₉H₂₆O₈

[ 分子量 ]:
382.405

[ 闪点 ]:
180.2±23.6 °C

[ 精确质量 ]:
382.162781

[ PSA ]:
114.82000

[ LogP ]:
-0.07

[ 蒸汽压 ]:
0.0±3.0 mmHg at 25°C

[ 折射率 ]:
1.578

[ 储存条件 ]:
2-8°C

新茄病镰刀菌烯醇MSDS

新茄病镰刀菌烯醇毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: YD0080000

CHEMICAL NAME :: Trichothec-9-ene-3-alpha,4-beta,8-alpha,15-tetrol, 12,13-epoxy-, 4,15-diacetate

CAS REGISTRY NUMBER :: 36519-25-2

LAST UPDATED :: 199612

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C19-H26-O8

MOLECULAR WEIGHT :: 382.45

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - guinea pig

REFERENCE :: FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 4,S124,1984 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 14500 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JJEMAG Japanese Journal of Experimental Medicine. (Kinokuniya Book-Stores of America Co., Ltd., West Bldg., Japan Cultural and Trade Center, 1581 Webster St., San Francisco, CA 94115) V.7- 1928- Volume(issue)/page/year: 42,187,1972

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 9700 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TOXIA6 Toxicon. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW, UK) V.1- 1962- Volume(issue)/page/year: 24,985,1986

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - chicken

DOSE/DURATION :: 24870 ug/kg

TOXIC EFFECTS :: Gastrointestinal - hypermotility, diarrhea Behavioral - muscle weakness Behavioral - food intake (animal)

REFERENCE :: AEMIDF Applied and Environmental Microbiology. (American Soc. for Microbiology, 1913 I St., NW, Washington, DC 20006) V.31- 1976- Volume(issue)/page/year: 35,636,1978

新茄病镰刀菌烯醇安全信息

[ 符号 ]:

GHS06

[ 信号词 ]:
Danger

[ 危害声明 ]:
H300 + H310 + H330

[ 警示性声明 ]:
P260-P264-P280-P284-P301 + P310-P302 + P350

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ 危害码 (欧洲) ]:
T+,Xn,F

[ 风险声明 (欧洲) ]:
26/27/28-36-20/21/22-11

[ 安全声明 (欧洲) ]:
22-36/37/39-45-36/37-16-26

[ 危险品运输编码 ]:
UN 2811 6.1/PG 1

[ WGK德国 ]:
3

[ RTECS号 ]:
YD0080000

[ 包装等级 ]:
I

[ 危险类别 ]:
6.1(a)

新茄病镰刀菌烯醇合成路线

新茄病镰刀菌烯醇上下游产品

新茄病镰刀菌烯醇上游产品

新茄病镰刀菌烯醇下游产品

新茄病镰刀菌烯醇文献

Toxicity induced by F. poae-contaminated feed and the protective effect of Montmorillonite supplementation in broilers.

Food Chem. Toxicol. 74 , 120-30, (2014)

The T-2 and HT-2 toxins, the main metabolites of Fusarium poae, induce toxicity in broilers and accumulate in tissues. Consequently, during the breeding process of broilers, diets are frequently suppl...

Key glycolytic enzyme activities of skeletal muscle are decreased under fed and fasted states in mice with knocked down levels of Shc proteins.

PLoS ONE 10(4) , e0124204, (2015)

Shc proteins interact with the insulin receptor, indicating a role in regulating glycolysis. To investigate this idea, the activities of key glycolytic regulatory enzymes and metabolites levels were m...

Hooking She3p onto She2p for myosin-mediated cytoplasmic mRNA transport.

Proc. Natl. Acad. Sci. U. S. A. 112(1) , 142-7, (2015)

The segregation of approximately two dozen distinct mRNAs from yeast mother to daughter cell cytoplasm is a classical paradigm for eukaryotic mRNA transport. The information for transport resides in a...

更多文献