5'-二磷酸鸟苷钠盐

5'-二磷酸鸟苷钠盐用途

鸟苷5'-二磷酸(GDP)钠是一种核苷二磷酸,可激活腺苷5'-三磷酸敏感的K+通道。鸟苷-5'-二磷酸钠是一种潜在的铁动员剂,可防止肝磷脂-铁蛋白相互作用,并调节白细胞介素-6(IL-6)/stat-3途径。鸟苷5'-二磷酸钠可用于炎症研究,如炎症性贫血[1][2]。

5'-二磷酸鸟苷钠盐名称

[ CAS 号 ]:
43139-22-6

[ 中文名 ]:
5’-二磷酸鸟苷钠盐

[ 英文名 ]:
guanosine 5'-diphosphate sodium salt

[中文别名 ]:

5'-二磷酸鸟苷钠盐

[英文别名 ]:

guanosine 5'-diphosphate sodium salt,Type I
GUANOSINE-5'-DIPHOSPHATE MONOSODIUM SALT
guanosine 5'-diphosphate sodium type I
5'-GDP 3NA
Guanosine-5''-diphosphoric acid monosodium salt

5'-二磷酸鸟苷钠盐生物活性

[ 描述 ]:

[ 相关类别 ]:

研究领域 >> 炎症/免疫

信号通路 >> 跨膜转运 >> 钾通道

[ 靶点 ]

Human Endogenous Metabolite

[参考文献]

[1]. S Kajioka, et al. Guanosine diphosphate activates an adenosine 5'-triphosphate-sensitive K+ channel in the rabbit portal vein. J Physiol. 1991 Dec;444:397-418.

[2]. Angmo S, et al. Identification of Guanosine 5'-diphosphate as Potential Iron Mobilizer: Preventing the Hepcidin-Ferroportin Interaction and Modulating the Interleukin-6/Stat-3 Pathway. Sci Rep. 2017 Jan 5;7:40097.

5'-二磷酸鸟苷钠盐物理化学性质

[ 分子式 ]:
C₁₀H₁₄N₅NaO₁₁P₂

[ 分子量 ]:
465.18200

[ 精确质量 ]:
465.00600

[ PSA ]:
275.02000

[ 外观性状 ]:
固体

[ 储存条件 ]:
20°C

5'-二磷酸鸟苷钠盐MSDS

详细MSDS(安全技术说明书)

5'-二磷酸鸟苷钠盐安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

5'-二磷酸鸟苷钠盐文献

A novel surface-confined glucaminium-based ionic liquid stationary phase for hydrophilic interaction/anion-exchange mixed-mode chromatography.

J. Chromatogr. A. 1360 , 240-7, (2014)

Glucaminium-based ionic liquids are a new class of recently developed ionic liquids and prepared by functionalizing the amine group of N-methyl-d-glucamine, which renders them good hydrophilicity due ...

ROS production in brown adipose tissue mitochondria: the question of UCP1-dependence.

Biochim. Biophys. Acta 1837(12) , 2017-30, (2014)

Whether active UCP1 can reduce ROS production in brown-fat mitochondria is presently not settled. The issue is of principal significance, as it can be seen as a proof- or disproof-of-principle concern...

Differential kinetics at PK/PEPCK branch point in the cestode, Raillietina echinobothrida.

Exp. Parasitol. 153 , 151-9, (2015)

Pyruvate kinase (PK; EC 2.7.1.40) and phosphoenolpyruvate carboxykinase (PEPCK; EC 4.1.1.32) are essential regulatory enzymes of glucose oxidation in helminths, the PK/PEPCK branch point being the fir...

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