美普卡因
美普卡因名称
[ CAS 号 ]:
495-70-5
[ 中文名 ]:
美普卡因
[ 英文名 ]:
Meprylcaine
[英文别名 ]:
- Benzoesaeure-(2-methyl-2-propylaminopropylester)
- Epirocaine
- Epirocain
- Meprylcainum [INN-Latin]
- Meprylcaine [INN]
- Oracaine
- 1-Benzoyloxy-2-methyl-2-propylamino-propan
- Meprilcaino [INN-Spanish]
- 2-Methyl-2-(propylamino)-1-propanol benzoate
- MEPRYLCAINE
美普卡因物理化学性质
[ 密度 ]:
1g/cm3
[ 沸点 ]:
329.5ºC at 760mmHg
[ 分子式 ]:
C14H21NO2
[ 分子量 ]:
235.32200
[ 闪点 ]:
153.1ºC
[ 精确质量 ]:
235.15700
[ PSA ]:
38.33000
[ LogP ]:
3.01250
[ 蒸汽压 ]:
0.000177mmHg at 25°C
[ 折射率 ]:
1.501
美普卡因毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UB8654200
- CHEMICAL NAME :
- 1-Propanol, 2-methyl-2-(propylamino)-, benzoate (ester)
- CAS REGISTRY NUMBER :
- 495-70-5
- BEILSTEIN REFERENCE NO. :
- 2581683
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C14-H21-N-O2
- MOLECULAR WEIGHT :
- 235.36
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 195 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - tremor
- REFERENCE :
- TOIZAG Toho Igakkai Zasshi. Journal of Medical Society of Toho University. (Toho Daigaku Igakkai, 21-16, Omori-nishi, 5-chome, Ota-ku, Tokyo 143, Japan) V.1- 1954- Volume(issue)/page/year: 9,38,1962
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 470 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - tremor
- REFERENCE :
- TOIZAG Toho Igakkai Zasshi. Journal of Medical Society of Toho University. (Toho Daigaku Igakkai, 21-16, Omori-nishi, 5-chome, Ota-ku, Tokyo 143, Japan) V.1- 1954- Volume(issue)/page/year: 9,38,1962
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 20 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - tremor
- REFERENCE :
- TOIZAG Toho Igakkai Zasshi. Journal of Medical Society of Toho University. (Toho Daigaku Igakkai, 21-16, Omori-nishi, 5-chome, Ota-ku, Tokyo 143, Japan) V.1- 1954- Volume(issue)/page/year: 9,38,1962
美普卡因合成路线
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