NG-硝基-D-精氨酸甲基酯盐酸盐

NG-硝基-D-精氨酸甲基酯盐酸盐用途

D-NAME hydrochloride (D-NG-nitroarginine methyl ester) 是一种有效的一氧化氮合酶 (NOS) 抑制剂。D-NAME hydrochloride 抑制 NOS 的活性,减少一氧化氮的产生。

NG-硝基-D-精氨酸甲基酯盐酸盐名称

[ CAS 号 ]:
50912-92-0

[ 中文名 ]:
NG-硝基-D-精氨酸甲基酯盐酸盐

[ 英文名 ]:
H-D-Arg(NO2)-Ome.HCl

[中文别名 ]:

[英文别名 ]:

MFCD00133613
NG-nitro-L-Arg-OMe*HCl
NG-Nitro-D-arginine methyl ester hydrochloride
H-Arg(NO2)-OMe.HCl
L-NAME (hydrochloride)
H-D-Arg(NO2)-OMe HCl
H-D-Arg(NO2)-Ome.HCl

NG-硝基-D-精氨酸甲基酯盐酸盐生物活性

[ 描述 ]:

D-NAME hydrochloride (D-NG-nitroarginine methyl ester) 是一种有效的一氧化氮合酶 (NOS) 抑制剂。D-NAME hydrochloride 抑制 NOS 的活性,减少一氧化氮的产生。

[ 相关类别 ]:

信号通路 >> 免疫及炎症 >> 一氧化氮合酶

研究领域 >> 神经疾病

[参考文献]

[1]. Palmer RM, et, al. L-arginine is the physiological precursor for the formation of nitric oxide in endothelium-dependent relaxation. Biochem Biophys Res Commun. 1988 Jun 30;153(3):1251-6.

NG-硝基-D-精氨酸甲基酯盐酸盐物理化学性质

[ 沸点 ]:
410.7ºC at 760 mmHg

[ 熔点 ]:
150-160 °C

[ 分子式 ]:
C₇H₁₆ClN₅O₄

[ 分子量 ]:
269.69

[ 闪点 ]:
202.2ºC

[ 精确质量 ]:
269.089081

[ PSA ]:
146.05000

[ LogP ]:
1.47960

[ 储存条件 ]:
−20°C

NG-硝基-D-精氨酸甲基酯盐酸盐MSDS

详细MSDS(安全技术说明书)

NG-硝基-D-精氨酸甲基酯盐酸盐安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 安全声明 (欧洲) ]:
S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ 海关编码 ]:
2925290090

NG-硝基-D-精氨酸甲基酯盐酸盐海关

[ 海关编码 ]: 2925290090

[ 中文概述 ]:
2925290090 其他亚胺及其衍生物，以及它们的盐。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:6.5%。普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2925290090 other imines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

NG-硝基-D-精氨酸甲基酯盐酸盐文献

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Radiology 251(3) , 697-704, (2009)

To determine whether a type of contrast medium (CM), iodixanol, modifies outer medullary descending vasa recta (DVR) vasoreactivity and nitric oxide (NO) production in isolated microperfused DVR.Anima...

Hyperglycemic myocardial damage is mediated by proinflammatory cytokine: macrophage migration inhibitory factor.

PLoS ONE 6 , e16239, (2011)

Diabetes has been regarded as an inflammatory condition which is associated with left ventricular diastolic dysfunction (LVDD). The purpose of this study was to examine the expression levels of macrop...

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