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N-乙酰-L-酪氨酸

N-乙酰-L-酪氨酸用途

N-Acetyl-L-tyrosine来源于AA乙酰酶作用下的酪氨酸,和芳香族氨基酸脱羧酶缺乏症以及酪氨酸血症有关。

N-乙酰-L-酪氨酸名称

[ CAS 号 ]:
537-55-3

[ 中文名 ]:
N-乙酰-L-酪氨酸

[ 英文名 ]:
N-Acetyl-L-tyrosine

[中文别名 ]:

[英文别名 ]:

L-Tyrosine, N-acetyl-
Ac-L-Tyr-OH
acetyl tyrosine
N-AC-L-TYR
(2S)-2-acetamido-3-(4-hydroxyphenyl)propanoic acid
N-Ac-Tyr
EINECS 208-671-3
n-acetyl-l-tyrosin
AC-TYR-OH
N-Acetyltyrosine

N-乙酰-L-酪氨酸生物活性

[ 描述 ]:

N-Acetyl-L-tyrosine来源于AA乙酰酶作用下的酪氨酸,和芳香族氨基酸脱羧酶缺乏症以及酪氨酸血症有关。

[ 相关类别 ]:

研究领域 >> 代谢疾病

天然产物 >> 其他

[ 靶点 ]

Human Endogenous Metabolite

[参考文献]

[1]. Abdenur JE, et al. Aromatic l-aminoacid decarboxylase deficiency: unusual neonatal presentation and additional findings in organic acid analysis. Mol Genet Metab. 2006 Jan;87(1):48-53.

[相关活性小分子]

N-乙酰-L-酪氨酸物理化学性质

[ 密度 ]:
1.3±0.1 g/cm3

[ 沸点 ]:
531.3±45.0 °C at 760 mmHg

[ 熔点 ]:
149-152 °C(lit.)

[ 分子式 ]:
C₁₁H₁₃NO₄

[ 分子量 ]:
223.225

[ 闪点 ]:
275.1±28.7 °C

[ 精确质量 ]:
223.084457

[ PSA ]:
86.63000

[ LogP ]:
0.04

[ 外观性状 ]:
白色至灰白色结晶粉末

[ 蒸汽压 ]:
0.0±1.5 mmHg at 25°C

[ 折射率 ]:
1.577

[ 储存条件 ]:
2-8°C

N-乙酰-L-酪氨酸MSDS

详细MSDS(安全技术说明书)

N-乙酰-L-酪氨酸安全信息

[ 符号 ]:

GHS05

[ 信号词 ]:
Danger

[ 危害声明 ]:
H318

[ 警示性声明 ]:
P280-P305 + P351 + P338 + P310

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xi:Irritant

[ 风险声明 (欧洲) ]:
R41

[ 安全声明 (欧洲) ]:
S26-S39

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ 海关编码 ]:
2924299090

N-乙酰-L-酪氨酸上下游产品

N-乙酰-L-酪氨酸上游产品

N-乙酰-L-酪氨酸下游产品

N-乙酰-L-酪氨酸海关

[ 海关编码 ]: 2924299090

[ 中文概述 ]:
2924299090. 其他环酰胺（包括环氨基甲酸酯）（包括其衍生物以及他们的盐）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 包装

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

N-乙酰-L-酪氨酸文献

Surfactants, aromatic and isoprenoid compounds, and fatty acid biosynthesis inhibitors suppress Staphylococcus aureus production of toxic shock syndrome toxin 1.

Antimicrob. Agents Chemother. 53 , 1898-906, (2009)

Menstrual toxic shock syndrome is a rare but potentially life-threatening illness manifest through the actions of Staphylococcus aureus toxic shock syndrome toxin 1 (TSST-1). Previous studies have sho...

Detection of autosomal dominant polycystic kidney disease by NMR spectroscopic fingerprinting of urine.

Kidney Int. 79(11) , 1244-53, (2011)

Autosomal dominant polycystic kidney disease (ADPKD) is a frequent cause of kidney failure; however, urinary biomarkers for the disease are lacking. In a step towards identifying such markers, we used...

Newborn screening for congenital adrenal hyperplasia: additional steroid profile using liquid chromatography-tandem mass spectrometry.

J. Clin. Endocrinol. Metab. 92(7) , 2581-9, (2007)

Neonatal screening programs for congenital adrenal hyperplasia (21-CAH) using an immunoassay for 17alpha-hydroxyprogesterone (17-OHP) generate a high rate of positive results attributable to physiolog...

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