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α-生育酚醋酸酯

α-生育酚醋酸酯用途

D-α-Tocopherol acetate (D-Vitamin E acetate) 可水解为 d-α-生育酚 (VE) 并被小肠吸收。

α-生育酚醋酸酯名称

[ CAS 号 ]:
58-95-7

[ 中文名 ]:
D-alpha-生育酚醋酸酯

[ 英文名 ]:
alpha-Tocopherol acetate

[中文别名 ]:

[英文别名 ]:

a-Tocopheryl Acetate
Vitamin E acetate
EINECS 231-710-0
Eprolin
Tocopheryl acetate
E-Vimin
Evion
MFCD00072052
Vitamin- E acetate
D-α-Tocopheryl acetate

α-生育酚醋酸酯生物活性

[ 描述 ]:

D-α-Tocopherol acetate (D-Vitamin E acetate) 可水解为 d-α-生育酚 (VE) 并被小肠吸收。

[ 相关类别 ]:

研究领域 >> 代谢疾病

[参考文献]

[1]. Fukui E, et al. Enhancing effect of medium-chain triglycerides on intestinal absorption of d-alpha-tocopherol acetate from lecithin-dispersed preparations in the rat. J Pharmacobiodyn. 1989 Feb;12(2):80-6.

α-生育酚醋酸酯物理化学性质

[ 密度 ]:
0.9±0.1 g/cm3

[ 沸点 ]:
184 ºC

[ 熔点 ]:
28 ºC

[ 分子式 ]:
C₃₁H₅₂O₃

[ 分子量 ]:
472.743

[ 闪点 ]:
235.6±24.7 °C

[ 精确质量 ]:
472.391632

[ PSA ]:
35.53000

[ LogP ]:
12.07

[ 外观性状 ]:
灰白色结晶固体

[ 蒸汽压 ]:
0.0±1.2 mmHg at 25°C

[ 折射率 ]:
1.488

[ 储存条件 ]:
存放于惰性气体之中;避免光,空气

[ 水溶解性 ]:
<0.1 g/100 mL at 17 ºC

α-生育酚醋酸酯MSDS

详细MSDS(安全技术说明书)

α-生育酚醋酸酯毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GP8280000

CHEMICAL NAME :: 6-Chromanol, 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, (+)-

CAS REGISTRY NUMBER :: 58-95-7

LAST UPDATED :: 199701

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C31-H52-O3

MOLECULAR WEIGHT :: 472.83

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 182 gm/kg/13W-C

TOXIC EFFECTS :: Liver - changes in liver weight Blood - pigmented or nucleated red blood cells Blood - changes in other cell count (unspecified)

REFERENCE :: FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 24,1043,1986 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 80575 No. of Facilities: 149 (estimated) No. of Industries: 3 No. of Occupations: 9 No. of Employees: 8005 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 80575 No. of Facilities: 834 (estimated) No. of Industries: 5 No. of Occupations: 9 No. of Employees: 8113 (estimated) No. of Female Employees: 5676 (estimated)

α-生育酚醋酸酯安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves

[ 安全声明 (欧洲) ]:
S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
1

[ RTECS号 ]:
GP8280000

α-生育酚醋酸酯上下游产品

α-生育酚醋酸酯上游产品

α-生育酚醋酸酯下游产品

α-生育酚醋酸酯制备

植醇与2，3，5-三甲基对苯二酚缩合，再与醋酐在锌及醋酸钠作用下制得。

α-生育酚醋酸酯文献

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