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4-甲基-7-氧香豆素-β-D-葡萄糖苷酸

4-甲基-7-氧香豆素-β-D-葡萄糖苷酸用途

4-甲基伞形花-β-D-葡糖苷酸是一种荧光底物(λex=362 nm,λem=445 nm)。4-甲基伞形花-β-D-葡萄糖醛酸在检测β-葡萄糖醛酸酶活性和大肠杆菌数量方面具有潜在的应用[1][2][3]。

4-甲基-7-氧香豆素-β-D-葡萄糖苷酸名称

[ CAS 号 ]:
6160-80-1

[ 中文名 ]:
4-甲基伞型酮-beta-D-葡糖苷酸

[ 英文名 ]:
4-Methylumbelliferylglucuronide

[中文别名 ]:

[英文别名 ]:

4-Methylumbelliferyl β-glucuronide
MFCD00036772
EINECS 228-186-0
4-Methylumbelliferyl-B-D-glucuronic acid
4-Methylumbelliferone β-D-glucuronide
4-Methylumbelliferylglucuronide
4-Methylumbelliferyl-β-D-glucuronide
4'-Methylumbelliferyl-ß-D-glucuronide

4-甲基-7-氧香豆素-β-D-葡萄糖苷酸生物活性

[ 描述 ]:

[ 相关类别 ]:

研究领域 >> 其他

[体外研究]

4-甲基伞形花-β-D-葡萄糖醛酸(156µM-5 mM；30分钟)在 37摄氏度下释放 4-甲基伞形酮,用于酶促反应[2]。 4-甲基伞形花-β-D-葡萄糖醛酸(50µg/mL；24小时)在坦桑尼亚联合共和国培养基中用于检测大肠杆菌数[3]。

[参考文献]

[1]. George I, et al. Use of beta-D-galactosidase and beta-D-glucuronidase activities for quantitative detection of totaland fecal coliforms in wastewater. Can J Microbiol. 2001 Jul;47(7):670-5.

[2]. Sperker B, et al. High-performance liquid chromatographic quantification of 4-methylumbelliferyl-beta-D-glucuronide as a probe for human beta-glucuronidase activity in tissue homogenates. J Chromatogr B Biomed Appl. 1996 Oct 11;685(1):181-4.

[3]. Villari P, et al. An evaluation of the use of 4-methylumbelliferyl-beta-D-glucuronide (MUG) in different solid media for the detection and enumeration of Escherichia coli in foods. Lett Appl Microbiol. 1997 Apr;24(4):286-90.

4-甲基-7-氧香豆素-β-D-葡萄糖苷酸物理化学性质

[ 密度 ]:
1.6±0.1 g/cm3

[ 沸点 ]:
683.1±55.0 °C at 760 mmHg

[ 熔点 ]:
102 °C

[ 分子式 ]:
C₁₆H₁₆O₉

[ 分子量 ]:
352.293

[ 闪点 ]:
255.0±25.0 °C

[ 精确质量 ]:
352.079437

[ PSA ]:
146.66000

[ LogP ]:
-0.63

[ 外观性状 ]:
白色至灰白色粉末

[ 蒸汽压 ]:
0.0±2.2 mmHg at 25°C

[ 折射率 ]:
1.664

[ 储存条件 ]:
2~8°C

[ 水溶解性 ]:
slightly soluble

4-甲基-7-氧香豆素-β-D-葡萄糖苷酸安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xi: Irritant;

[ 风险声明 (欧洲) ]:
R22

[ 安全声明 (欧洲) ]:
S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

4-甲基-7-氧香豆素-β-D-葡萄糖苷酸合成路线

详细合成路线

4-甲基-7-氧香豆素-β-D-葡萄糖苷酸上下游产品

4-甲基-7-氧香豆素-β-D-葡萄糖苷酸上游产品

4-甲基-7-氧香豆素-β-D-葡萄糖苷酸下游产品

4-甲基-7-氧香豆素-β-D-葡萄糖苷酸文献

Development of an enzyme assay for rapid assessment of Escherichia coli in seawaters.

J. Appl. Microbiol. 93(4) , 548-56, (2002)

An analytical protocol has been developed and applied for the detection of glucuronidase activity in marine waters as a rapid alternative approach to assess the microbiological quality of seawaters.Th...

An alternative approach for enumeration of Escherichia coli in foods.

Int. J. Food Microbiol. 68(3) , 217-23, (2001)

An assay to screen Escherichia coli in foods using MUG supplemented lauryl sulfate tryptose (LST) broth instead of tryptone water (TW) medium was evaluated. The results presented in this paper suggest...

Serogroup distribution and virulence characteristics of sorbitol-negative Escherichia coli from food and cattle stool.

J. Appl. Microbiol. 108(2) , 658-65, (2010)

To (i) study the serogroup distribution and virulence characteristics of non-sorbitol-fermenting Escherichia coli isolates from foods of animal origin and cattle faeces and (ii) re-examine the true so...

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