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生物氯菊酯

生物氯菊酯用途

trans-Permethrin 是 Permethrin (HY-B0887) 的反式构型。Permethrin 是一种杀虫剂和神经毒素。

生物氯菊酯名称

[ CAS 号 ]:
61949-77-7

[ 中文名 ]:
生物氯菊酯

[ 英文名 ]:
trans-permethrin

[中文别名 ]:

反式苄氯菊酯

[英文别名 ]:

EINECS 263-347-9
MFCD00145431
trans-Permethrin solution

生物氯菊酯生物活性

[ 描述 ]:

trans-Permethrin 是 Permethrin (HY-B0887) 的反式构型。Permethrin 是一种杀虫剂和神经毒素。

[ 相关类别 ]:

研究领域 >> 神经疾病

[参考文献]

[1]. Xiao X, et al. Exposure to permethrin promotes high fat diet-induced weight gain and insulin resistance in male C57BL/6J mice. Food Chem Toxicol. 2018 Jan;111:405-416.

[2]. Smith LB, et al. CYP-mediated permethrin resistance in Aedes aegypti and evidence for trans-regulation. PLoS Negl Trop Dis. 2018 Nov 19;12(11):e0006933.

生物氯菊酯物理化学性质

[ 密度 ]:
1.293g/cm3

[ 沸点 ]:
465.9ºC at 760 mmHg

[ 分子式 ]:
C₂₁H₂₀Cl₂O₃

[ 分子量 ]:
391.28800

[ 闪点 ]:
-18ºC

[ 精确质量 ]:
390.07900

[ PSA ]:
35.53000

[ LogP ]:
6.11330

[ 折射率 ]:
1.615

[ 储存条件 ]:
APPROX 4°C

生物氯菊酯MSDS

详细MSDS(安全技术说明书)

生物氯菊酯毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GZ1251580

CHEMICAL NAME :: Cyclopropanecarboxylic acid, 3-(2,2-dichloroethenyl)-2,2-dimethyl-, (3-phenoxyphenyl) methyl ester, trans-

CAS REGISTRY NUMBER :: 61949-77-7

LAST UPDATED :: 199510

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C21-H20-Cl2-O3

MOLECULAR WEIGHT :: 391.31

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >800 mg/kg

TOXIC EFFECTS :: Behavioral - altered sleep time (including change in righting reflex) Behavioral - tremor

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 66,153,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >135 mg/kg

TOXIC EFFECTS :: Behavioral - altered sleep time (including change in righting reflex) Behavioral - tremor

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 66,153,1982 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 53,329,1991 IARC Cancer Review:Human No Available Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 53,329,1991 IARC Cancer Review:Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 53,329,1991

生物氯菊酯安全信息

[ 符号 ]:

GHS02, GHS07, GHS08, GHS09

[ 信号词 ]:
Danger

[ 危害声明 ]:
H225-H304-H315-H336-H410

[ 警示性声明 ]:
P210-P261-P273-P301 + P310-P331-P501

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
F,Xn,N

[ 风险声明 (欧洲) ]:
11-38-50/53-65-67

[ 安全声明 (欧洲) ]:
S60;S61;S62

[ 危险品运输编码 ]:
UN 1145 3/PG 2

生物氯菊酯文献

Plant essential oils affect the toxicities of carbaryl and permethrin against Aedes aegypti (Diptera: Culicidae).

J. Med. Entomol. 50(4) , 826-32, (2013)

ABSTRACT Phytochemicals have been considered as alternatives for conventional pesticides because of their low mammalian toxicity and environmental safety. They usually display less potent insecticidal...

Field-collected permethrin-resistant Aedes aegypti from central Thailand contain point mutations in the domain IIS6 of the sodium channel gene (KDR).

Southeast Asian J. Trop. Med. Public Health 43(6) , 1380-6, (2012)

One of the mechanisms responsible for pyrethroid resistance in mosquitoes is mutations in domain IIS6 of voltage-gated sodium channel gene (kdr). Aedes aegypti larvae were collected from the central p...

Efficacy of three insecticides against Anopheles dirus and Anopheles minimus, the major malaria vectors, in Kanchanaburi Province, Thailand.

Southeast Asian J. Trop. Med. Public Health 43(6) , 1339-45, (2012)

We conducted this study to determine the insecticide susceptibility of two malaria vectors, Anopheles dirus and Anopheles minimus from Kanchanaburi Province, Thailand. The mosquitoes were collected an...

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