N-N-Propylformamide

N-N-Propylformamide名称

[ CAS 号 ]:
6281-94-3

[ 英文名 ]:
N-N-Propylformamide

[英文别名 ]:

N-N-Propylformamide物理化学性质

[ 密度 ]:
0.865g/cm3

[ 沸点 ]:
197.2ºC at 760 mmHg

[ 分子式 ]:
C4H9NO

[ 分子量 ]:
87.12040

[ 闪点 ]:
96.8ºC

[ 精确质量 ]:
87.06840

[ PSA ]:
29.10000

[ LogP ]:
1.16920

[ 折射率 ]:
1.399

N-N-Propylformamide毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :
LQ3325000
CHEMICAL NAME :
Formamide, N-n-propyl-
CAS REGISTRY NUMBER :
6281-94-3
BEILSTEIN REFERENCE NO. :
1739276
LAST UPDATED :
199612
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C4-H9-N-O
MOLECULAR WEIGHT :
87.14
WISWESSER LINE NOTATION :
VHM3

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
440 mg/kg
TOXIC EFFECTS :
Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Sense Organs and Special Senses (Eye) - effect, not otherwise specified Behavioral - somnolence (general depressed activity)
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 26,596,1973
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
380 mg/kg
TOXIC EFFECTS :
Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Sense Organs and Special Senses (Eye) - effect, not otherwise specified Behavioral - somnolence (general depressed activity)
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 26,596,1973 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
180 mg/kg/36D-I
TOXIC EFFECTS :
Kidney, Ureter, Bladder - other changes in urine composition Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Biochemical - Metabolism (Intermediary) - Plasma proteins not involving coagulation
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 26,596,1973

N-N-Propylformamide合成路线

详细合成路线

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