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DL-3-(3,4-二羟苯基)丙氨酸

DL-3-(3,4-二羟苯基)丙氨酸用途

DL-Dopa是苯丙氨酸的β-羟基化衍生物。

DL-3-(3,4-二羟苯基)丙氨酸名称

[ CAS 号 ]:
63-84-3

[ 中文名 ]:
DL-3-(3,4-二羟苯基)丙氨酸

[ 英文名 ]:
DL-Dopa

[中文别名 ]:

[英文别名 ]:

EINECS 200-566-0
<small>DL</small>-3-(3,4-Dihydroxyphenyl)alanine
MFCD00063060
Tyrosine, 3-hydroxy-

DL-3-(3,4-二羟苯基)丙氨酸生物活性

[ 描述 ]:

DL-Dopa是苯丙氨酸的β-羟基化衍生物。

[ 相关类别 ]:

研究领域 >> 其他

天然产物 >> 其他

[ 靶点 ]

Human Endogenous Metabolite

[参考文献]

[1]. Yen HC, et al. Effects of various drugs on 3,4-dihydroxyphenylalanine (DL-DOPA)-induced excitation (agressive behavior) in mice. Toxicol Appl Pharmacol. 1970 Nov;17(3):597-604.

[相关活性小分子]

DL-3-(3,4-二羟苯基)丙氨酸物理化学性质

[ 密度 ]:
1.468 g/cm3

[ 沸点 ]:
448.39ºC at 760 mmHg

[ 熔点 ]:
270-272ºC(lit.)

[ 分子式 ]:
C₉H₁₁NO₄

[ 分子量 ]:
197.18800

[ 闪点 ]:
224.978ºC

[ 精确质量 ]:
197.06900

[ PSA ]:
103.78000

[ LogP ]:
0.75250

[ 储存条件 ]:
室温

DL-3-(3,4-二羟苯基)丙氨酸MSDS

详细MSDS(安全技术说明书)

DL-3-(3,4-二羟苯基)丙氨酸毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AY5250000

CHEMICAL NAME :: Alanine, 3-(3,4-dihydroxyphenyl)-, DL-

CAS REGISTRY NUMBER :: 63-84-3

LAST UPDATED :: 199504

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C9-H11-N-O4

MOLECULAR WEIGHT :: 197.21

WISWESSER LINE NOTATION :: QVYZ1R CQ DQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD691-490 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X1293 No. of Facilities: 10 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 59 (estimated) No. of Female Employees: 59 (estimated)

DL-3-(3,4-二羟苯基)丙氨酸安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
AY5250000

DL-3-(3,4-二羟苯基)丙氨酸上下游产品

DL-3-(3,4-二羟苯基)丙氨酸上游产品

DL-3-(3,4-二羟苯基)丙氨酸下游产品

DL-3-(3,4-二羟苯基)丙氨酸文献

Bone metastases radiopharmaceuticals: an overview.

Curr. Radiopharm. 6(1) , 41-7, (2013)

The skeleton is one of the preferential sites for metastases of solid tumors, and metastatic disease is the most common malignancy of the bone. Diagnosis and evaluation of skeletal metastases require ...

Stability of polydopamine and poly(DOPA) melanin-like films on the surface of polymer membranes under strongly acidic and alkaline conditions

Colloids Surf. B Biointerfaces 110 , 22-8, (2013)

This study investigated the stability of polydopamine and poly(3,4-dihydroxyphenylalanine) (poly(DOPA)) melanin-like films on the surface of polymer substrates. Three polymer membranes, polypropylene ...

Mussel adhesion is dictated by time-regulated secretion and molecular conformation of mussel adhesive proteins.

Nat. Commun. 6 , 8737, (2015)

Interfacial water constitutes a formidable barrier to strong surface bonding, hampering the development of water-resistant synthetic adhesives. Notwithstanding this obstacle, the Asian green mussel Pe...

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