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石榴皮鞣素

石榴皮鞣素用途

Punicalin 是一种可水解的单宁,可从 Punica granatum L. 或 Terminalia catappa L. 的叶子中分离。Punicalin 是一种抗乙型肝炎病毒 (HBV) 药物,具有抗炎活性。

石榴皮鞣素名称

[ CAS 号 ]:
65995-64-4

[ 中文名 ]:
石榴皮鞣素

[ 英文名 ]:
punicalin

[中文别名 ]:

[英文别名 ]:

punicalin
gn-30

石榴皮鞣素生物活性

[ 描述 ]:

Punicalin 是一种可水解的单宁,可从 Punica granatum L. 或 Terminalia catappa L. 的叶子中分离。Punicalin 是一种抗乙型肝炎病毒 (HBV) 药物,具有抗炎活性。

[ 相关类别 ]:

研究领域 >> 感染

信号通路 >> 抗感染 >> HBV

研究领域 >> 炎症/免疫

[参考文献]

[1]. Lin CC, et al. Effects of punicalagin and punicalin on carrageenan-induced inflammation in rats. Am J Chin Med. 1999;27(3-4):371-6.

[2]. Liu C, et al. Identification of hydrolyzable tannins (punicalagin, punicalin and geraniin) as novel inhibitors of hepatitis B virus covalently closed circular DNA. Antiviral Res. 2016 Oct;134:97-107.

石榴皮鞣素物理化学性质

[ 密度 ]:
2.1±0.1 g/cm3

[ 沸点 ]:
1559.6±65.0 °C at 760 mmHg

[ 分子式 ]:
C₃₄H₂₂O₂₂

[ 分子量 ]:
782.525

[ 闪点 ]:
484.7±27.8 °C

[ 精确质量 ]:
782.060242

[ PSA ]:
385.24000

[ LogP ]:
1.24

[ 蒸汽压 ]:
0.0±0.3 mmHg at 25°C

[ 折射率 ]:
1.872

[ 储存条件 ]:
-20°C

石榴皮鞣素安全信息

[ 危险品运输编码 ]:
NONH for all modes of transport

石榴皮鞣素文献

Effects of pomegranate chemical constituents/intestinal microbial metabolites on CYP1B1 in 22Rv1 prostate cancer cells.

J. Agric. Food Chem. 57(22) , 10636-44, (2009)

The cytochrome P450 enzyme, CYP1B1, is an established target in prostate cancer chemoprevention. Compounds inhibiting CYP1B1 activity are contemplated to exert beneficial effects at three stages of pr...

A new method of standartization of health-promoting pomegranate fruit (Punica granatum) extract.

Georgian Med. News (140) , 70-7, (2006)

This study analyzes the major phenolic constituents of pomegranate fruit juice and pericarp feedstock, and dry extracts thereof, using high-performance liquid chromatography. Pomegranate pericarp was ...

Antioxidant and hepatoprotective effects of punicalagin and punicalin on acetaminophen-induced liver damage in rats.

Phytother Res. 15(3) , 206-12, (2001)

Punicalagin and punicalin were isolated from the leaves of Terminalia catappa L., a Combretaceous plant distributed throughout tropical and subtropical beaches, which is used for the treatment of derm...

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