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异贝壳杉烯酸, 贝壳杉烯酸

异贝壳杉烯酸, 贝壳杉烯酸用途

Kaurenoic acid 是一种来源 Sphagneticola trilobata 的二萜,能通过抑制细胞因子的产生和激活 NO–cyclic GMP–PKG–ATP- 敏感型钾通道信号通路来抑制炎症疼痛。

异贝壳杉烯酸, 贝壳杉烯酸名称

[ CAS 号 ]:
6730-83-2

[ 中文名 ]:
贝壳杉烯酸

[ 英文名 ]:
Kaurenoic acid

[中文别名 ]:

[英文别名 ]:

Kaurenoic acid
Cunabic acid
(5β,8α,9β,10α,13α)-Kaur-16-en-18-oic acid
(5β,8α,9β,10α)-Kaur-16-en-18-oic acid
KAUREN-19-OIC ACID
Kaurane-16-ene-18-oic acid
ent-kaur-16-en-19-oic acid

异贝壳杉烯酸, 贝壳杉烯酸生物活性

[ 描述 ]:

Kaurenoic acid 是一种来源 Sphagneticola trilobata 的二萜,能通过抑制细胞因子的产生和激活 NO–cyclic GMP–PKG–ATP- 敏感型钾通道信号通路来抑制炎症疼痛。

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

研究领域 >> 炎症/免疫

研究领域 >> 神经疾病

[参考文献]

[1]. Mizokami SS, et al. Kaurenoic acid from Sphagneticola trilobata Inhibits Inflammatory Pain: effect on cytokine production and activation of the NO-cyclic GMP-protein kinase G-ATP-sensitive potassium channel signaling pathway. J Nat Prod. 2012 May 25;75(5):896-904.

异贝壳杉烯酸, 贝壳杉烯酸物理化学性质

[ 密度 ]:
1.1±0.1 g/cm3

[ 沸点 ]:
426.6±34.0 °C at 760 mmHg

[ 分子式 ]:
C₂₀H₃₀O₂

[ 分子量 ]:
302.451

[ 闪点 ]:
202.8±20.3 °C

[ 精确质量 ]:
302.224579

[ PSA ]:
37.30000

[ LogP ]:
6.37

[ 外观性状 ]:
粉末

[ 蒸汽压 ]:
0.0±2.2 mmHg at 25°C

[ 折射率 ]:
1.550

[ 储存条件 ]:
?20°C

异贝壳杉烯酸, 贝壳杉烯酸MSDS

详细MSDS(安全技术说明书)

异贝壳杉烯酸, 贝壳杉烯酸安全信息

[ 危险品运输编码 ]:
NONH for all modes of transport

异贝壳杉烯酸, 贝壳杉烯酸文献

Development and validation of two methods based on high-performance liquid chromatography-tandem mass spectrometry for determining 1,2-benzopyrone, dihydrocoumarin, o-coumaric acid, syringaldehyde and kaurenoic acid in guaco extracts and pharmaceutical preparations.

J. Sep. Sci. 34(7) , 740-8, (2011)

In this study, two HPLC-ESI-MS/MS methods were developed and validated for the determination of 1,2-benzopyrone (COU), o-coumaric acid (OCA), kaurenoic acid (KAU), syringaldehyde (SYR), and dihydrocou...

Anticonvulsant effect of kaurenoic acid isolated from the root bark of Annona senegalensis.

Pharmacol. Biochem. Behav. 109 , 38-43, (2013)

The herbal preparations of Annona senegalensis Pers. (Annonaceae) root bark are used in Nigerian ethnomedicine for the treatment of epilepsy and febrile seizures. The scientific evidence for this effe...

Biosynthesis of uterotonic diterpenes from Montanoa tomentosa (zoapatle).

J. Plant Physiol. 166(18) , 1961-7, (2009)

Montanoa tomentosa (zoapatle) is a Central American plant used in Mexico in traditional herbal medicine to ease childbirth labor and to cure certain female disorders. Recently, crude extracts of M. to...

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