盐酸小檗碱水合物

Berberine chloride hydrate是从一些植物中提取的生物碱,具有多种生物功能,包括胰岛素敏化,抗炎和抗氧化活性。它是 AMPK 的活化剂。

信号通路 >> 干细胞及 Wnt 通路 >> β-catenin

信号通路 >> 自噬 >> 自噬

信号通路 >> 干细胞及 Wnt 通路 >> Wnt信号

研究领域 >> 癌症

[1]. Albring KF, et al. Berberine acts as a natural inhibitor of Wnt/β-catenin signaling--identification of more active 13-arylalkyl derivatives. Biofactors. 2013 Nov-Dec;39(6):652-62.

[2]. Jabbarzadeh Kaboli P, et al. Targets and mechanisms of berberine, a natural drug with potential to treat cancer with special focus on breast cancer. Eur J Pharmacol. 2014 Jun 26. pii: S0014-2999(14)00467-1.

[3]. Wang Y, et al. Berberine decreases cholesterol levels in rats through multiple mechanisms, including inhibition of cholesterol absorption. Metabolism. 2014 Jun 4. pii: S0026-0495(14)00162-0.

[4]. Yu R, et al. Berberine-induced apoptotic and autophagic death of HepG2 cells requires AMPK activation. Cancer Cell Int. 2014 Jun 11;14:49.

XAV-939 | 2,3-二氢-1,4-苯并恶嗪 | 盐霉素 | IWR-1-endo | Wnt-C59 | 扑蛲灵 | ETC-159 | CID11210285 盐酸盐 | IWP 2 | 硫酸类肝素 | KYA1797K | 2,5-二氯-N-(2-甲基-4-硝基苯基)苯磺酰胺 | SKL2001 | 8-[3-氯-5-[4-(1-甲基-1H-吡唑-4-基)苯基]-4-吡啶基]-2,8-二氮杂螺[4.5]癸烷-1-酮 | iCRT 14