3-(2-(4-(4-氟苯甲酰基)哌啶-1-基)乙基)-2-甲基-4H-吡啶并[1,2-a]嘧啶-4-酮

吡伦哌酮(R 47465)是一种5-HT2血清素受体拮抗剂。吡仑贝隆具有适度的抗焦虑活性[1][2]。

[ 描述 ]:

[ 相关类别 ]:

[参考文献]

[ 密度 ]:
1.26g/cm3

[ 沸点 ]:
556.3ºC at 760 mmHg

[ 分子式 ]:
C₂₃H₂₄FN₃O₂

[ 分子量 ]:
393.45

[ 闪点 ]:
290.2ºC

[ 精确质量 ]:
393.18500

[ PSA ]:
54.68000

[ LogP ]:
3.21730

[ 折射率 ]:
1.629

[ 储存条件 ]:
室温，干燥，密封

详细MSDS(安全技术说明书)

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xi

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

详细合成路线

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5-HT inhibits spontaneous contractility of isolated sheep mesenteric lymphatics via activation of 5-HT(4) receptors.

Microvasc. Res. 60(3) , 261-8, (2000)

Spontaneous isometric contractions were measured in rings of sheep mesenteric lymphatic vessels in vitro. 5-Hydroxytryptamine (5-HT) produced a concentration-dependent decrease in spontaneous contract...

Monoamine systems in the discriminative effects of spiradoline, a kappa-opioid agonist.

Pharmacol. Biochem. Behav. 47(3) , 575-8, (1994)

The results of studies on mice indicate that the antinociceptive effects of kappa-opioid agonists are due, in part, to activation of the 5-HT2 type of serotonin receptor. One objective of this study w...

Visual recognition memory in squirrel monkeys: effects of serotonin antagonists on baseline and hypoxia-induced performance deficits.

Pharmacol. Biochem. Behav. 39(4) , 991-6, (1991)

Cognitive deficits resulting from neuropathological brain changes such as Alzheimer's Disease or normal aging are most likely due to alterations in multiple neurotransmitter systems. While the majorit...

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公司名：上海化源世纪贸易有限公司

区域：上海市普陀区

价格：

联系人：徐经理

产品详情：3-(2-(4-(4-氟苯甲酰基)哌啶-1-基)乙基)-2-甲基-4H-吡啶并[1,2-a]嘧啶-4-酮

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公司名：上海阿拉丁生化科技股份有限公司

区域：上海市浦东新区

价格：
￥648.9/5mg ￥7136.9/100mg ￥2265.9/25mg ￥需询单/1g

联系人：阿拉丁

产品详情：肾上腺素

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