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香叶基焦磷酸铵盐

香叶基焦磷酸铵盐用途

香叶基二磷酸是类异戊二烯生物合成途径中的关键中间体。HY-114295在细胞代谢中起关键作用,并负责生成甾醇和非甾醇类异戊二烯[1][2]。

香叶基焦磷酸铵盐名称

[ CAS 号 ]:
763-10-0

[ 中文名 ]:
香叶基焦磷酸铵盐

[ 英文名 ]:
GERANYL PYROPHOSPHATE AMMONIUM 200

[英文别名 ]:

geraniol pyrophosphate
geranylpyrophosphate
geranyl azide
Geranyl diphosphate
2,6-Octadiene,1-azido-3,7-dimethyl-,(2E)

香叶基焦磷酸铵盐生物活性

[ 描述 ]:

香叶基二磷酸是类异戊二烯生物合成途径中的关键中间体。HY-114295在细胞代谢中起关键作用,并负责生成甾醇和非甾醇类异戊二烯[1][2]。

[ 相关类别 ]:

研究领域 >> 代谢疾病

[ 靶点 ]

Human Endogenous Metabolite

[体外研究]

香叶基二磷酸是一种类异戊二烯(IsoP),参与许多不同的细胞过程,包括胆固醇合成[1]。

[参考文献]

[1]. Chhonker YS, et, al. Simultaneous Quantitation of Isoprenoid Pyrophosphates in Plasma and Cancer Cells Using LC-MS/MS. Molecules. 2018 Dec 11;23(12):3275.

[2]. Chang TH, et, al. Structure of a heterotetrameric geranyl pyrophosphate synthase from mint (Mentha piperita) reveals intersubunit regulation. Plant Cell. 2010 Feb;22(2):454-67.

香叶基焦磷酸铵盐物理化学性质

[ 密度 ]:
1.342g/cm3

[ 沸点 ]:
484.2ºC at 760 mmHg

[ 分子式 ]:
C₁₀H₂₀O₇P₂

[ 分子量 ]:
314.20900

[ 闪点 ]:
20ºC

[ 精确质量 ]:
314.06800

[ PSA ]:
132.91000

[ LogP ]:
2.90540

[ 折射率 ]:
1.51

香叶基焦磷酸铵盐MSDS

详细MSDS(安全技术说明书)

香叶基焦磷酸铵盐安全信息

[ 符号 ]:

GHS02, GHS06, GHS08

[ 信号词 ]:
Danger

[ 危害声明 ]:
H225-H301 + H311 + H331-H370

[ 警示性声明 ]:
P210-P260-P280-P301 + P310-P311

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
F,T

[ 风险声明 (欧洲) ]:
11-39/23/24/25-23/24/25

[ 安全声明 (欧洲) ]:
7-16-23-45-36/37

[ 危险品运输编码 ]:
UN 1230 3/PG 2

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香叶基焦磷酸铵盐文献

In vitro and in vivo anticancer effects of mevalonate pathway modulation on human cancer cells.

Br. J. Cancer 111(8) , 1562-71, (2014)

The increasing usage of statins (the 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors) has revealed a number of unexpected beneficial effects, including a reduction in cancer risk.We investi...

Transcriptome profiling provides new insights into the formation of floral scent in Hedychium coronarium.

BMC Genomics 16 , 470, (2015)

Hedychium coronarium is a popular ornamental plant in tropical and subtropical regions because its flowers not only possess intense and inviting fragrance but also enjoy elegant shape. The fragrance r...

Identification, Functional Characterization, and Evolution of Terpene Synthases from a Basal Dicot.

Plant Physiol. 169 , 1683-97, (2015)

Bay laurel (Laurus nobilis) is an agriculturally and economically important dioecious tree in the basal dicot family Lauraceae used in food and drugs and in the cosmetics industry. Bay leaves, with th...

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