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4-硼-L-苯基丙氨酸

4-硼-L-苯基丙氨酸用途

(S) -2-氨基-3-(4-硼苯基)丙酸是一种生物化学试剂,可作为生物材料或有机化合物用于生命科学相关研究。

4-硼-L-苯基丙氨酸名称

[ CAS 号 ]:
76410-58-7

[ 中文名 ]:
4-硼-L-苯丙氨酸

[ 英文名 ]:
4-Borono-L-phenylalanine

[中文别名 ]:

[英文别名 ]:

(2S)-2-amino-3-(4-boronophenyl)propanoic acid
Phenylalanine, 4-borono-
MFCD01075172
4-(dihydroxyboranyl)-L-phenylalanine
L-Phenylalanine, 4-borono-
4-(Dihydroxyboryl)phenylalanine
p-Borono-L-phenylalanine

4-硼-L-苯基丙氨酸生物活性

[ 描述 ]:

(S) -2-氨基-3-(4-硼苯基)丙酸是一种生物化学试剂,可作为生物材料或有机化合物用于生命科学相关研究。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

4-硼-L-苯基丙氨酸物理化学性质

[ 密度 ]:
1.3±0.1 g/cm3

[ 沸点 ]:
449.3±55.0 °C at 760 mmHg

[ 熔点 ]:
285-293ºC (dec.)

[ 分子式 ]:
C₉H₁₂BNO₄

[ 分子量 ]:
209.01

[ 闪点 ]:
225.5±31.5 °C

[ 精确质量 ]:
209.085938

[ PSA ]:
103.78000

[ LogP ]:
0.49

[ 外观性状 ]:
固体;White to Light yellow powder to crystal

[ 蒸汽压 ]:
0.0±1.2 mmHg at 25°C

[ 折射率 ]:
1.591

[ 储存条件 ]:
2-8°C

4-硼-L-苯基丙氨酸MSDS

4-硼-L-苯基丙氨酸安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi: Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
26-36-37/39

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ 海关编码 ]:
2931900090

4-硼-L-苯基丙氨酸合成路线

4-硼-L-苯基丙氨酸上下游产品

4-硼-L-苯基丙氨酸上游产品

4-硼-L-苯基丙氨酸下游产品

4-硼-L-苯基丙氨酸海关

[ 海关编码 ]: 2931900090

[ 中文概述 ]:
2931900090. 其他有机-无机化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:AB(入境货物通关单,出境货物通关单). 最惠国关税:6.5%. 普通关税:30.0%

[ Summary ]:
2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0%

4-硼-L-苯基丙氨酸文献

Pharmacokinetic analysis and uptake of 18F-FBPA-Fr after ultrasound-induced blood-brain barrier disruption for potential enhancement of boron delivery for neutron capture therapy.

J. Nucl. Med. 55(4) , 616-21, (2014)

Boronophenylalanine has been applied in clinical boron neutron capture therapy for the treatment of high-grade gliomas. The purpose of this study was to evaluate the pharmacokinetics of 4-borono-2-(18...

Low dose of gamma irradiation enhanced boronophenylalanine uptake in head and neck carcinoma cells for boron neutron capture therapy.

Appl. Radiat. Isot. 69(12) , 1728-31, (2011)

This study attempted to increase the boron uptake of human head and neck carcinoma SAS cells for BNCT by using a gamma dose of 0.1 Gy for combined treatment. Intracellular boron concentrations in 25 μ...

Boron neutron capture therapy induces apoptosis of glioma cells through Bcl-2/Bax.

BMC Cancer 10 , 661, (2010)

Boron neutron capture therapy (BNCT) is an alternative treatment modality for patients with glioma. The aim of this study was to determine whether induction of apoptosis contributes to the main therap...

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