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DL-高胱氨酸

DL-高胱氨酸用途

DL-Homocystine 是由两分子同型半胱氨酸组成的,同型半胱氨酸被认为在精神分裂症的发病机制和病理生理学中有着很重要的作用。

DL-高胱氨酸名称

[ CAS 号 ]:
870-93-9

[ 中文名 ]:
DL-高胱氨酸

[ 英文名 ]:
4,4'-Dithiobis[2-aminobutyric Acid]

[中文别名 ]:

[英文别名 ]:

H-DL-Hcys-OH)2
Dl-Homocycine
EINECS 207-323-8
homocystine
4,4'-Disulfanediylbis(2-aminobutanoic acid)
MFCD00069587
4,4'-Disulfanediylbis(2-aminobutansäure)
Butanoic acid, 4,4'-dithiobis[2-amino-
dl-homocystine crystalline
HOMOCYSTINE,DL

DL-高胱氨酸生物活性

[ 描述 ]:

DL-Homocystine 是由两分子同型半胱氨酸组成的,同型半胱氨酸被认为在精神分裂症的发病机制和病理生理学中有着很重要的作用。

[ 相关类别 ]:

研究领域 >> 代谢疾病

天然产物 >> 其他

[ 靶点 ]

Human Endogenous Metabolite

[参考文献]

[1]. Brown AS, et al. Homocysteine and schizophrenia: from prenatal to adult life. Prog Neuropsychopharmacol Biol Psychiatry. 2005 Sep;29(7):1175-80.

[相关活性小分子]

DL-高胱氨酸物理化学性质

[ 密度 ]:
1.4±0.1 g/cm3

[ 沸点 ]:
507.6±50.0 °C at 760 mmHg

[ 熔点 ]:
≥300 °C

[ 分子式 ]:
C₈H₁₆N₂O₄S₂

[ 分子量 ]:
268.354

[ 闪点 ]:
260.8±30.1 °C

[ 精确质量 ]:
268.055145

[ PSA ]:
177.24000

[ LogP ]:
1.03

[ 外观性状 ]:
白色至略米色固体

[ 蒸汽压 ]:
0.0±2.8 mmHg at 25°C

[ 折射率 ]:
1.619

[ 储存条件 ]:
室温

[ 稳定性 ]:
Stable. Incompatible with strong oxidizing agents.

DL-高胱氨酸MSDS

详细MSDS(安全技术说明书)

DL-高胱氨酸安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ 海关编码 ]:
2930909090

DL-高胱氨酸制备

1. 用丙二酸酯方法合成。从3,6-双（β-氯乙基）-2,5-哌嗪二酮合成。

DL-高胱氨酸海关

[ 海关编码 ]: 2930909090

[ 中文概述 ]:
2930909090. 其他有机硫化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

DL-高胱氨酸文献

Determination of homocysteine in cerebrospinal fluid as an indicator for surgery treatment in patients with hydrocefalus.

Physiol. Res. 63(4) , 521-7, (2014)

Increased homocysteine levels in serum are typical features of neurodegenerative brain diseases including hydrocephalus. The most frequent therapeutic approach consists of the insertion of a shunt, co...

Simultaneous determination of cystathionine, total homocysteine, and methionine in dried blood spots by liquid chromatography/tandem mass spectrometry and its utility for the management of patients with homocystinuria.

Clin. Chim. Acta 437 , 211-7, (2014)

Disorders of homocysteine and B-vitamin metabolism represent a significant problem in clinical practice. Establishing the diagnosis requires specialized tests with demanding preanalytical requirements...

Excess levels of cysteine and homocysteine induce tibial dyschondroplasia in broiler chicks.

J. Nutr. 122 , 482-487, (1992)

The effect of excessive levels of cysteine and homocysteine on tibial dyschondroplasia (TD) in broiler chicks was studied. In the first experiment, graded levels of L-cysteine as well as one level of ...

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